血清HGB、SA、STP水平与老年重症肺炎患者病情及预后的相关性分析

Correlation Analysis of Serum HGB,SA,STP Levels with the Condition and Prognosis of Elderly Patients with Severe Pneumonia

目的分析血清血红蛋白(HGB)、白蛋白(SA)、总蛋白(STP)水平与老年重症肺炎患者病情及预后的相关性。方法选取2020年1月至2022年12月郑州大学第一附属医院收治的90例老年重症肺炎患者,按照是否存在多器官功能障碍综合征(MODS)分为合并MODS组与无MODS组,同时根据其28 d内预后情况将患者分为死亡组与存活组,评估其临床肺部感染(CPIS)评分、急性生理学与慢性健康状况评分系统Ⅱ评分(APACHEⅡ),检测血清HGB、SA、STP水平,进行相关性分析。结果合并MODS组与无MODS组STP水平比较差异无统计学意义(P>0.05);合并MODS组HGB、SA水平低于无MODS组(P<0.05)。老年重症肺炎患者血清HGB、SA水平与CPIS评分、APACHEⅡ评分呈负相关(P<0.05);死亡组与存活组STP水平比较差异无统计学意义(P>0.05);死亡组血清HGB、SA水平低于存活组(P<0.05);血清HGB、SA水平与患者预后呈正相关(P<0.05)。结论血清HGB、SA水平与老年重症肺炎患者病情程度及预后密切相关。

Objective To analyze the correlation of serum hemoglobin(HGB),serum albumin(SA),serum total protein(STP)levels with the condition and prognosis of elderly patients with severe pneumonia.Methods A total of 90 elderly patients with severe pneumonia treated in the First Affiliated Hospital of Zhengzhou University from January 2020 to December 2022 were enrolled.According to the presence or absence of multiple organ dysfunction syndrome(MODS),they were divided into MODS group and non-MODS group.According to the 28-day prognosis,they were divided into death group and survival group.The clinical pulmonary infection score(CPIS)and acute physiology and chronic health evaluationⅡscore(APACHEⅡ)were assessed.Serum HGB,SA and STP levels were detected,and correlation analysis was conducted.Results There was no statistical difference in STP level between MODS group and non-MODS group(P>0.05).The levels of HGB and SA in MODS group were lower than those in non-MODS group(P<0.05).Serum HGB and SA levels were negatively correlated with CPIS and APACHEⅡscore(P<0.05).There was no statistical difference in STP level between death group and survival group(P>0.05).Serum HGB and SA levels in death group were lower than those in survival group(P<0.05).Serum HGB and SA levels were positively correlated with the prognosis(P<0.05).Conclusion Serum HGB and SA levels are closely related to the condition and prognosis of elderly patients with severe pneumonia.