左心耳封堵术后新发残余分流的研究进展

Research progress of new-onset peridevice leak after left atrial appendage closure procedure

卒中预防作为心房颤动治疗的三驾马车之一,始终处在临床研究和实践的焦点。对于非瓣膜性心房颤动,约90%血栓来源于左心耳,经导管左心耳封堵术这一非药物血栓预防手段便应运而生。然而正如抗凝药物易引发出血等不良反应,左心耳封堵术后最常见的并发症便是器械周围的残余分流,目前尚未真正了解到这一并发症的临床危害,但有必要对存在残余分流的患者给予针对性的随访和管理保驾。本文对左心耳封堵术后新发残余分流的相关进展进行综述。

As one of the three main treatment strategy in atrial fibrillation,management of stroke prevention has always been the focus in clinical study and practice.To patients who have been diagnosed with non-valvular atrial fibrillation,almost 90%of clots are located in the left atrial appendage.Therefore,left atrial appendage closure,a non-pharmaceutical therapy for stroke prevention,enters our vision.The most common complication of LAA closure is peridevice leak,just as bleeding to oral anticoagulation drug,nevertheless,it’s still not clear and definite whether this leak may increase thromboembolism or other risk.Even so,we should bear in mind that it is essential to provide targeted follow-up and antithrombotic management for people with leakage.This article reviews the development of new-onset peridevice leak after left atrial appendage closure procedure.