红藤败酱汤加减治疗慢性盆腔炎的临床效果分析

Analysis of clinical effect of modified Hongteng Baijiang Decoction on chronic pelvic inflammatory disease

目的分析慢性盆腔炎患者应用红藤败酱汤加减治疗的临床价值。方法选取74例慢性盆腔炎患者为研究对象,借助随机数字表法分为对照组和观察组,每组37例。对照组患者采用西药治疗,观察组患者在对照组基础上运用中医药红藤败酱汤加减治疗。对比两组患者临床疗效,施治前后中医证候积分、血清炎症因子水平和药物不良反应发生率。结果施治后,两组患者中医证候积分均明显低于本组施治前,且观察组患者中医证候积分(2.05±0.13)分明显低于对照组的(5.17±1.06)分,差异有统计学意义(P<0.05)。观察组患者治疗总有效率97.30%高于对照组的83.78%,差异有统计学意义(P<0.05)。施治后,观察组患者血清肿瘤坏死因子-α(TNF-α)(32.06±5.33)fmol/ml、C反应蛋白(CRP)(7.06±1.05)mg/L均低于对照组的(45.26±6.19)fmol/ml、(9.63±1.22)mg/L,差异有统计学意义(P<0.05)。两组患者药物不良反应发生率对比,差异无统计学意义(P>0.05)。结论慢性盆腔炎患者应用红藤败酱汤加减治疗能有效改善患者临床症状,进一步提升临床疗效,且有助于抑制机体炎症反应,用药安全性较高。

Objective To analyze the clinical value of modified Hongteng Baijiang Decoction on chronic pelvic inflammatory disease.Methods A total of 74 patients with chronic pelvic inflammatory disease were selected as the study subjects,and were divided into control group and observation group according to the random numerical table,with 37 cases in each group.The control group was treated with western medicine,and the observation group was treated with modified Hongteng Baijiang Decoction on the basis of the control group.The clinical efficacy,traditional Chinese medicine syndrome score,serum inflammatory factor level before and after treatment,and incidence of adverse drug reactions were compared between the two groups.Results After treatment,traditional Chinese medicine syndrome score in both groups were significantly lower than that before treatment in this group;the traditional Chinese medicine syndrome score of(2.05±0.13)points in the observation group was significantly lower than that of(5.17±1.06)points in the control group;the differences were statistically significant(P<0.05).The total effective rate of 97.30%in the observation group was higher than that of 83.78%in the control group,and the difference was statistically significant(P<0.05).After treatment,the observation group had serum tumor necrosis factor-α(TNF-α)of(32.06±5.33)fmol/ml and C-reactive protein(CRP)of(7.06±1.05)mg/L,which were lower than those of(45.26±6.19)fmol/ml and(9.63±1.22)mg/L in the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse drug reactions between the two groups(P>0.05).Conclusion The application of modified Hongteng Baijiang Decoction in the treatment of patients with chronic pelvic inflammatory disease can effectively improve the clinical symptoms of patients,further enhance the clinical efficacy,and help to inhibit the body inflammatory response,with high drug safety.