2007—2016年江苏省苏州市居民恶性肿瘤发病及生存分析

Incidence and Survival of Malignant Tumors in Suzhou Residents of Jiangsu Province from 2007 to 2016

[目的]分析2007-2016年苏州市居民恶性肿瘤发病及5年生存情况。[方法]收集苏州市慢性病监测系统2007年1月至2016年12月恶性肿瘤患者登记资料,随访截止日期为2021年12月31日。使用SAS 9.4和Stata 15.0软件进行分析,计算粗发病率和标化发病率,应用寿命表法计算观察生存率,EdererⅡ法计算相对生存率,相对生存标化采用国际癌症生存标准进行调整。采用平均年度变化百分比(AAPC)分析变化趋势。[结果] 2007-2016年间苏州市居民恶性肿瘤发病数合计112 351例,粗发病率为343.65/10万,中标率为196.07/10万,男性粗发病率高于女性。2007-2016年间苏州市居民全部恶性肿瘤5年观察生存率为36.9%,5年相对生存率为40.4%,其中男性5年相对生存率为35.8%,女性5年相对生存率为45.2%。2007-2016年苏州市居民胰腺癌、肝癌、肺癌5年相对生存率较低,女性乳腺癌、甲状腺癌5年相对生存率较高;女性(AAPC=3.5%,P<0.001)、全人群(AAPC=2.2%,P=0.008)恶性肿瘤5年相对生存率呈逐年递增趋势。[结论] 2007-2016年苏州市居民恶性肿瘤5年相对生存率呈逐年递增趋势,但恶性肿瘤发病率较高,胰腺癌、肝癌、肺癌5年相对生存率依然较低,应重点关注其高危人群的癌症筛查情况,降低其发病及死亡水平。

[Purpose]To analyze the incidence of malignant tumors and survival of patients in Suzhou City of Jiangsu Province from 2007 to 2016.[Methods]The data of new cases of malig-nant tumors during January 2007 to December 2016 were collected from Suzhou Cancer Registry and patients were followed-up till 31 December,2021.The overall survival rate(OSR)and relative survival rate(RSR)were calculated by the Life-table program and EdererⅡmethod.Statistical analysis were performed with Stata 15.0 and SAS 9.4 software.Standardized survival rate was ad-justed by international cancer survival criteria.The average annual percentage change(AAPC)was used to analyze trends in change.[Results]A total of 112351 cases of malignant tumors were registered in Suzhou City from 2007 to 2016.The crude incidence was 343.65/105 and the age-standardized incidence rate by Chinese standard population(ASIRC)was 196.07/105.The crude incidence was higher in male than that in female(χ2=1726.330,P<0.001),The 5-year OSR was 36.9%and the 5-year RSR was 40.4%;the 5-year RSR for male and females was 35.8%and 45.2%,respectively.The 5-year RSR of pancreatic cancer,liver cancer and lung cancer was low,while that of female breast cancer and thyroid cancer was high.The 5-year RSR showed an increasing trend both for females(AAPC=3.5%,P<0.001)and whole population(AAPC=2.2%,P=0.008).[Conclusion]From 2007 to 2016,the incidence of malignant tumors was relatively high in Suzhou City,but the 5-year RSR showed an upward trend.However,the 5-year RSR of pan-creatic cancer,liver cancer and lung cancer was still low;therefore,the cancer screening of high-risk groups should be focused on to reduce their incidence and death.