针灸治疗膝骨关节炎临床选穴规律

Clinical Acupoint Selection Law of Acupuncture and Moxibustion for Knee Osteoarthritis

目的:通过数据挖掘技术探究针灸治疗膝骨关节炎的临床选穴及组方规律。方法:通过检索中国知网、万方数据知识服务平台、维普资讯中文期刊服务平台、中国生物医学文献数据库(SinoMed)、PubMed中针灸治疗膝骨关节炎的临床文献,建立针灸处方数据库,运用Microsoft Excel 2010进行描述统计;SPSS Modeler 18.0进行关联规则分析;Cytoscape 3.9.1绘制高频腧穴共现网络图;SPSS Statistics 21.0进行聚类分析。结果:最终提取有效针灸处方432个,涉及72个腧穴。高频腧穴为犊鼻、内膝眼、阳陵泉等;归经多取足阳明胃经、足太阴脾经;特定穴中合穴使用居多;核心腧穴组合为犊鼻-内膝眼;腧穴主要分布在下肢部;以近部选穴为主,结合远部选穴。结论:针灸治疗膝骨关节炎选穴有一定的规律性与集中性,可为日后临床治疗膝骨关节炎的规范选穴提供参考。

Objective:To explore the clinical acupoint selection and prescription rule of acupuncture and moxibustion in the treatment of knee osteoarthritis through data mining technology.Methods:The clinical literature of acupuncture and moxibustion treatment of knee osteoarthritis in China HowNet,Wanfang Data Knowledge Service Platform,VIP Information Chinese Periodical Service Platform,China Biomedical Literature Database(SinoMed)and PubMed were searched,and the acupuncture prescription database was established,and the description and statistics were made by using Microsoft Excel 2010.SPSS Modeler 18.0 is used to analyze association rules;Cytoscape 3.9.1 draw the network diagram of high-frequency acupoint co-occurrence;SPSS Statistics 21.0 was used for cluster analysis.Results:Finally,432 effective acupuncture prescriptions were extracted,involving 72 acupoints.The high-frequency acupoints are Dubi,Neixiyan,Yanglingquan,etc.Meridian tropism mainly includes Stomach meridian of Foot Yangming and Spleen meridian of Foot Taiyin.The He acupoint in special points is mostly used;The combination of core acupoints is calf nose-inner knee eye;Acupoints are mainly distributed in the lower limbs;Acupoint selection is mainly based on the proximal part and combined with the distal part.Conclusion:Acupuncture treatment of knee osteoarthritis has certain regularity and concentration,which can provide reference for standardized acupoint selection in clinical treatment of knee osteoarthritis in the future.