内科支架复合材料的制备与老化性能

Preparation and aging properties of medical stent composites

内科支架是医疗上组织缺损修复技术中的1种,内科支架复合材料在人体内受血液脉冲、浸泡等会出现老化现象,为充分掌握其老化程度,研究内科支架复合材料的制备与老化性能。通过制备PLCL/Col混合溶液,使用LDM系统通过调整打印3D打印参数后,打印内科支架复合材料,再通过测定内科支架复合材料表观老化、力学老化、孔隙率、亲水率等数值,分析内科支架复合材料老化性能。实验结果表明:内科支架复合材料表面覆膜随着老化时间的增加会出现起翘、表面破损情况,其内部纤维也会出现变细、断裂情况,导致内科支架复合材料稳定性降低;其亲水触角也随着老化时间的增加而降低,疏水性能降低等。

The medical stent is one of the medical tissue defect repair technologies.The medical stent composite material will age when it is subjected to blood pulse and immersion in the human body.In order to fully grasp its aging degree,the preparation and aging performance of the medical stent composite material are studied.By preparing the PLCL/col mixed solution,using the LDM system to adjust the printing 3D printing parameters,print the medical stent composite,and then analyze the aging performance of the medical stent composite by measuring the apparent aging,mechanical aging,porosity,hydrophilicity and other values of the medical stent composite.The experimental results show that with the increase of aging time,the film covering on the surface of the medical stent composite will appear warping and surface damage,and its internal fiber will also appear thinning and fracture,leading to the reduction of the stability of the medical stent composite;Its hydrophilic contact angle also decreases with the increase of aging time,and its hydrophobic property decreases.