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Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation

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摘要 Dear Editor,Aquareovirus(ARV,Reoviridae)causes hemorrhagic disease in the economically important golden shiner and grass carp of America and China,respectively(Nason et al.,2000;Fang et al.,2005).Reoviridae members are characterized by endogenous transcription of their multipartite genomes within capsids of 1-3 layers and are further classified based on the presence(Spinareovirinae subfamily,9 genera)or absence(Sedoreovirinae subfamily,6 genera)of mRNA-capping turrets along the innermost layer(King et al.,2012).
出处 《Protein & Cell》 SCIE CSCD 2023年第7期546-550,共5页 蛋白质与细胞(英文版)
基金 supported in part by grants from the National Institutes of Health(AI094386 to Z.H.Z.) A.S.received support from NIH Ruth L.Kirschtein National Research Service Award A1007323 We acknowledge the use of resource at the Electron Imaging Center for Nanomachines supported by UCLA and by instrumentation grants from NIH(1S10RR23057,1S100D018111 and U24GM116792) NSF(DBI-1338135 and DMR-1548924) at the UCLA AIDS Institute supported in part by UCLA-CDU CFAR(NIH AI152501)。
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