丝素蛋白水凝胶在骨组织工程中的研究进展

Research progress on application of silk fibroin hydrogel in bone tissue engineering

首先介绍了丝素蛋白水凝胶的物理、化学制备方法及原理;然后介绍了几种不同性状的丝素蛋白水凝胶;最后重点介绍了丝素蛋白水凝胶及其联合因子、干细胞在骨组织工程中的应用,并对其发展进行了总结与展望。

This review firstly introduces the physical,chemical preparation methods and the principles for crosslinked silk fibroin hydrogels.It also introduces several silk fibroin hydrogels with different properties.Finally,it emphasizes the application of silk fibroin hydrogels,its combination factors and stem cells in bone tissue engineering,and summarizes and predicts the development of silk fibroin hydrogels.