老年结直肠癌肠造口者术后早期衰弱状况及其影响因素分析

Postoperatively Early Hyposthenia Situation of Senior Colorectal Cancer Patients Underwent Ostomy,and an analysis on the Influence Factors

目的:探讨老年结直肠癌肠造口者术后早期衰弱发生状况及其影响因素。方法:选择2019年3月至2022年3月我院70例老年结直肠癌肠造口术后早期患者,收集其临床资料,采用Tilburg衰弱量表评估患者衰弱状况,采用造口患者生活质量问卷(QOL-OQ)评估患者生活质量,采用匹兹堡睡眠质量指数(PSQI)评估患者睡眠质量,采用焦虑自评量表(SAS)评价患者焦虑情况。分析患者生活质量、睡眠质量、焦虑情绪等与术后早期衰弱的相关性,并采用多重线性回归分析法分析影响衰弱的因素。结果:本组患者术后早期衰弱发生率为92.9%(65/70),Tilburg衰弱量表评分平均(7.96±1.53)分。不同年龄、文化程度、婚姻状况、家庭收入水平、伴发疾病、并发症、自觉健康状况组患者Tilburg衰弱量表评分比较差异均有统计学意义,P<0.05;QOL-OQ评分与Tilburg衰弱量表评分呈负相关,PSQI、SAS评分与Tilburg衰弱量表评分呈正相关,P<0.001。多重线性回归分析,高龄、文化程度低、已婚、收入水平低、伴发多种疾病、存在造口并发症、自觉健康状况差、生活质量差、睡眠质量差、焦虑是结直肠癌术后早期衰弱的危险因素,P<0.001。结论:老年结直肠癌肠造口者术后早期衰弱普遍存在,这种衰弱受多种因素影响,临床应有针对性的予以干预。

Objective To investigate postoperatively early hyposthenia situation of senior colorectal cancer patients underwent ostomy, and analyse the influence factors. Methods Enrolled 70 cases met above conditions in authors' hospital(2019-03-2022-03) into this research: collect their clinical data, by using Tilburg hyposthenia scale evaluate their hyposthenia situation, adopting QOL-OQ evaluate their quality of life, adopting PSQI evaluate their sleep quality, and adopting SAS evaluate their anxiety status.Then, analyse the relativity of quality of life, sleep quality and anxiety emotion to postoperatively early hyposthenia, and, by using Multi-linear regression analysis method analyse the factors influencing hyposthenia. Results In the 70 cases, the incidence of the hyposthenia was 92.9%(65/70),the average points from Tilburg hyposthenia scale were(7.96±1.53) points which had statistical difference between the patients having different age, educated levels, marrige situation, family income levels, complicated diseases, complication, and subjective health situation(P<0.05),and, were negatively related to QOL-OQ ratings, also proportionally related to PSQI and SAS ratings(P<0.001).Multi-linear regression analysis showed advanced age, low educated level, marriged, less income, complicated many diseases, with stomy-related complications, bad subjective health situation, poor quality of life, poor sleep quality, and being anxiety were the risk factors influencing postoperative early hyposthenia of colorectal cancer patients with stoma(P<0.001). Conclusion In the senior colorectal cancer patients underwent ostomy postoperative early hyposthenia is common which are influenced by many factors, thus, clinically, it should be to take targeted intervention.