CT引导下脓肿引流术治疗肺脓肿对患者炎性因子水平的改善评价

Evaluation of improvement of inflammatory factor levels in patients with pulmonary abscess by CT-guided abscess drainage

目的探讨CT引导下脓肿引流术治疗肺脓肿对患者炎性因子水平的改善作用。方法选择2019年1月—2022年1月收治的60例肺脓肿患者为研究对象,随机分为对照组(30例)和观察组(30例)。对照组给予药物治疗,观察组给予CT引导下脓肿引流术治疗。对比两组的机体症状表现消失时间、住院时长及炎性因子水平改善情况。结果治疗后,观察组的咳嗽时间为(11.16±1.45)d、高热表现消失时间为(7.15±0.46)d及脓肿吸收开始时间为(8.14±1.05)d,均相对短于对照组,其住院时长为(4.16±0.64)d,亦相对短于对照组,P<0.05。治疗后,两组的各项炎症因子指标数值水平均低于治疗前,且观察组的降钙素原[(81.15±4.16)ng/L]、白细胞介素-6[(11.15±1.76)ng/L]及C-反应蛋白[(7.14±0.49)mg/L]指标数值水平均低于对照组,P<0.05。结论CT引导下脓肿引流术治疗肺脓肿可明显加快患者的机体症状表现改善速度,缩短住院时长,降低炎性因子水平,值得进行推广应用。

Objective To investigate the effect of CT-guided abscess drainage in the treatment of pulmonary abscess on the levels of inflammatory factors in patients.Methods A total of 60 patients diagnosed with lung abscess were selected to participate in the study from January 2019 to January 2022.They were randomly divided into a control group(30 cases)and an observation group(30 cases).The control group was given drug therapy and the observation group was given CT-guided abscess drainage,respectively.The disappearance time of symptoms,length of hospital stay,and the improvement of inflammatory factor levels were compared between the two groups.Results After treatment,the cough time[(11.16±1.45)d],disappearance time of high fever[(7.15±0.46)d],abscess absorption start time[(8.14±1.05)d],and length of hospital stay[(4.16±0.46)d]in the observation group were all shorter than those in the control group(P<0.05).After treatment,the levels of various inflammatory factors in the two groups were lower than those before treatment,and the levels of procalcitonin[(81.15±4.16)ng/L],interleukin-6[(11.15±1.76)ng/L],and C-reactive protein[(7.14±0.49)mg/L]in the observation group were lower than those in the control group(P<0.05).Conclusion CT-guided abscess drainage in the treatment of lung abscess can significantly speed up the improvement of patients’symptoms,shorten the length of hospital stay,and reduce the levels of inflammatory factors,which is worthy of popularization and application.