氨茶碱治疗蛛网膜下腔阻滞麻醉后头痛的效果观察

Efficacy of aminophylline on spinal anesthesia-induced headache

目的观察氨茶碱治疗蛛网膜下腔阻滞麻醉后头痛的效果。方法选取2019年6月1日至2021年10月30日该院收治的53例蛛网膜下腔阻滞麻醉后头痛患者,将其随机分为氨茶碱组(26例)和对照组(27例)。氨茶碱组患者给予氨茶碱200 mg静脉滴注,对照组给予等量生理盐水静脉滴注。观察输注后0 min(T_(0))、30 min(T_(1))、60 min(T_(2))两组患者的疼痛视觉模拟评分法(VAS)评分、血流动力学参数及患者和医疗团队对治疗效果的满意度情况。结果氨茶碱组T_(1)、T_(2)的VAS评分均低于T_(0)(P<0.05)。氨茶碱组T_(1)、T_(2)的VAS评分均低于对照组(P<0.05)。氨茶碱组T_(0)收缩压/T_(2)收缩压的比值和T_(0)心率/T_(2)心率的比值均高于对照组,差异均有统计学意义(P<0.05)。氨茶碱组治疗后镇痛药物使用率及住院时间明显低于对照组(P<0.05)。氨茶碱组患者和医疗团队对治疗效果的满意度评分均高于对照组(P<0.05)。结论静脉滴注氨茶碱可快速有效地缓解蛛网膜下腔阻滞麻醉后头痛,改善患者的血流动力学参数,减少镇痛药物的使用、缩短患者的住院时间,患者及医疗团队均对治疗效果满意。

Objective To observe efficacy of aminophylline on spinal anesthesia-induced headache.Methods A total of 53 patients with headache after spinal anesthesia admitted to this hospital from June 1,2019 to October 30,2021 were randomly divided into aminophylline group(26 cases)and control group(27 cases).The aminophylline group was given aminophylline 200 mg by intravenous drip,and the control group was given the same amount of normal saline by intravenous drip.The visual analogue scale(VAS)scores,hemodynamic parameters,patients and care team satisfaction situation of treatment effectiveness in both groups were evaluated at 0 min(T_(0)),30 min(T_(1))and 60 min(T_(2))after infusion.Results VAS scores at T_(1) and T_(2) were lower than those at T_(0) in aminophylline group(P<0.05).The VAS scores at T_(1) and T_(2) in aminophylline group were lower than those in control group(P<0.05).The ratios of T_(0) systolic blood pressure to T_(2) systolic blood pressure and T_(0) heart rate to T_(2) heart rate in the aminophylline group were higher than those in the control group,and the differences were statistically significant(P<0.05).The propotion of patients using analgesics and the hospital stay in the aminophylline group were significantly lower than those in the control group(P<0.05).The satisfaction scores of patients and care team to treatment effectiveness in aminophylline group were higher than those in conrtol group(P<0.05).Conclusion Aminophylline can effectively relieve spinal anesthesia-induced headache with better hemodynamic parameters and reduce the use of analgesics and the hospital stay with user friendliness.Both patients and care team have good satisfaction with the treatment effect.