番茄红素生物合成及抗氧化研究进展

Advances on Lycopene Biosynthesis and Antioxidant Research

番茄红素属于异戊二烯类化合物,存在于番茄、红胡萝卜等蔬菜水果中。因其特殊的化学结构被认为是一种有效的抗氧化剂,可有效地提高自身组织、细胞的抗氧化能力,调节免疫系统能力,有效维持人体健康及氧化应激介导的功能障碍。文章综述了番茄红素的结构和生物利用度、番茄红素的生物合成和番茄红素的抗氧化生物活性,并阐述了番茄红素的代谢途径和通过基因工程等手段构建工程菌生产番茄红素的研究进展,为番茄红素的工业化生产、高效利用和功能挖掘提供了参考。

Lycopene is a isoprene compound abundantly found in tomatoes,carrots and other vegetables or fruits.For its special chemical structure,it is considered as an effective antioxidant,which can effectively improve the antioxidant capacity of its own tissues and cells,enhance the ability of the immune system,and effectively maintain human health and oxidative stress-mediated dysfunction.This review describes the structure and bioavailability,the biosynthesis and the antioxidant bioactivity of lycopene,expounds the metabolic pathway of lycopene and the research progress of lycopene production by genetic engineering,which provides a reference for the industrial production,efficient utilization and functional mining of lycopene.