1.5T MR多序列在前列腺增生与前列腺癌诊断中应用的价值研究

Research on the Value of 1.5T MR Multi-sequence in the Diagnosis of Benign Prostatic Hyperplasia and Prostate Cancer

目的 分析1.5T磁共振成像(magnetic resonance imaging,MR)多序列在前列腺增生和前列腺癌诊断中应用的价值。方法将2019年1月—2022年12月在南京市六合区人民医院接受检查的34例疑似前列腺增生患者和32例疑似前列腺癌患者作为研究对象。所有患者均使用西门子1.5T MR多序列检查,其中包含常规序列、常规序列+频率衰减反转恢复序列(spectral attenuated inversion recovery,SPAIR)扫描、常规序列+弥散加权成像(diffusion weighted imaging,DWI)扫描、常规序列+SPAIR+DWI扫描4种检查方式,以病理检查为金标准。统计4种检查方式在前列腺增生和前列腺癌疾病诊断中应用的结果及表现,并运用ROC曲线进行详细分析。结果 常规序列+SPAIR+DWI扫描在前列腺增生和前列腺癌疾病诊断中的阳性检出率高于其他序列扫描的检出结果,且结果更接近于金标准。常规序列+SPAIR+DWI扫描诊断前列腺增生的AUC为0.801,诊断前列腺癌的AUC为0.799,差异有统计学意义(P<0.05)。结论 经西门子1.5T MR多序列检查方式的4种检查类型运用到前列腺增生与前列腺癌诊断中,可见常规序列+SPAIR+DWI扫描在前列腺增生和前列腺癌诊断中应用的结果更接近于金标准。

Objective Analyze the value of 1.5T magnetic resonance imaging(MR) multiple sequences in the diagnosis of prostate hyperplasia and prostate cancer.Methods 34 suspected prostate hyperplasia patients and 32 suspected prostate cancer patients who underwent examinations at the People's Hospital of Liuhe District,Nanjing from January 2019 to December 2022 were selected as the study subjects.All patients underwent Siemens 1.5T MR multi-sequence examination,which included four examination methods:conventional sequence,conventional sequence+frequency attenuated inversion recovery(SPAIR) scan,conventional sequence+diffusion weighted imaging(DWI)scan,and conventional sequence+SPAIR+DWI scan,with pathological examination as the gold standard.Statistical analysis of the results and manifestations of four examination methods in the diagnosis of prostate hyperplasia and prostate cancer,and detailed analysis using ROC curves.Results The positive detection rate of conventional sequence+SPAIR+DWI scanning in the diagnosis of prostate hyperplasia and prostate cancer diseases was higher than that of other sequence scans,and the results were closer to the gold standard.The AUC of conventional sequence+SPAIR+DWI scan for diagnosing benign prostatic hyperplasia was 0.801,while the AUC of prostate cancer was 0.799,the difference was statistically significant(P<0.05).Conclusion The application of four types of Siemens 1.5T MR multi sequence examination in the diagnosis of prostate hyperplasia and prostate cancer shows that the results of conventional sequence+SPAIR+DWI scanning in the diagnosis of prostate hyperplasia and prostate cancer are closer to the gold standard.