化疗联合免疫疗法治疗胃癌的临床疗效分析

Clinical Efficacy Analysis of Chemotherapy Combined with Immunotherapy in the Treatment of Gastric Cancer

目的 分析化疗联合免疫治疗对胃癌患者的临床效果。方法 便利选取2022年1月—2023年1月吉林省肿瘤医院收治的胃癌患者104例,采用随机数字抽签法分为两组,每组52例,对照组实施化疗,观察组在对照组基础上配合免疫治疗,比较两组循环肿瘤细胞检测结果、免疫功能指标与临床疗效。结果 治疗后研究组循环肿瘤细胞检测结果低于对照组,差异有统计学意义(P<0.05);治疗后研究组各项免疫功能指标均高于对照组,差异有统计学意义(P<0.05);治疗后研究组有效率为98.08%,高于对照组的78.85%,差异有统计学意义(χ^(2)=9.420,P<0.05)。结论 化疗联合免疫疗法治疗胃癌患者的临床效果显著,可以有效降低循环肿瘤细胞,有效防止患者肿瘤出现复发转移的情况。

Objective To analyze the clinical efficacy of chemotherapy combined with immunotherapy on patients with gastric cancer.Methods A total of 104 gastric cancer patients admitted to Jilin Province Cancer Hospital from January 2022 to January 2023 were conveniently selected and divided into two groups by random number drawing method,with 52 cases in each group.The control group received chemotherapy,and the study group was combined with immunotherapy on the basis of the control group.The detection results of circulating tumor cells,immune function indexes and clinical efficacy of the two groups were compared.Results After treatment,the detection result of circulating tumor cells in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the immune function indexes of the study group were higher than those of the control group,and the difference was statistically significant(P<0.05).After treatment,the effective rate of the study group was 98.08%,which was higher than 78.85% of the control group,and the difference was statistically significant(χ^(2)=9.420,P<0.05).Conclusion Chemotherapy combined with immunotherapy has a significant clinical effect in the treatment of gastric cancer patients,can effectively reduce circulating tumor cells,and effectively prevent tumor recurrence and metastasis in patients.