白血病患儿癌因性疲乏管理的最佳证据总结

Best evidence summary of cancer-related fatigue in children with leukemia

目的评价总结白血病患儿癌因性疲乏管理相关的最佳证据,为临床实践提供循证依据。方法运用循证护理学方法计算机检索UpToDate、JBI循证卫生保健中心、Cochrane Library、加拿大安大略护理学会、国际指南网、英国国家卫生与临床优化研究所、美国国立指南库、医脉通指南网、美国国立综合癌症网络、PubMed、CINAHL、荷兰医学文摘数据库、中国知网、万方、中国生物医学文献数据库。检索时限为2012年1月1日至2022年5月1日,由2名研究者采用统一评价标准进行独立评价文献质量并提取最佳证据。结果共纳入文献13篇,其中临床指南3篇,证据总结2篇,系统评价8篇,最终形成包括环境管理、癌因性疲乏评估、运动管理、冒险疗法、睡眠管理和心理社会干预共6个方面22条最佳证据。结论最佳证据可用于白血病患儿癌因性疲乏管理,应用时需结合环境、患儿的年龄、体能、病情、心理接受能力等制订个体化的症状管理方案,提高护理质量及患儿生命质量。

Objective To evaluate and summarize the best evidence related to the management of cancer-related fatigue in children with leukemia and provide an evidence-based basis for clinical practice.Methods The search for the relevant guidelines and evidence synthesis from UpToDate,JBI,Cochrane Library,Registered Nurses′Association of Ontario,Guidelines International Network,National Institute for Health and Clinical Excellence,National Guideline Clearinghouse,YiMaiTong Guideline Network,National Comprehensive Cancer Network,PubMed,CINAHL,EMbase,China National Knowledge Infrastructure,Wanfang,China Biology Medicine from January 1st,2012 to May 1st,2022.Two researchers evaluated the quality of the literature independently according to the unified standard and extracted the best evidence.Results A total of 13 literatures were extracted,including three clinical practice guidelines,two evidence summaries and eight systematic reviews.Finally,22 pieces of evidence were summarized,involving six aspects which were environmental management,cancer-related fatigue assessment,exercise management,adventure therapy,sleep management and psychosocial interventions.Conclusions Best evidence for the management of cancer-related fatigue in children with leukemia,which should be used in conjunction with the environment,the child's age,physical ability,medical condition and psychological acceptability to develop an individualized symptom management plan to improve the quality of care and the child′s quality of life.