摘要
克罗恩病(CD)是一种病因及发病机制尚不明确的慢性非特异性肠道炎性疾病。CD患者发生肛周病变概率高,肛周病变是CD患者长期不良预后的独立因素。对直肠肛周CD患者需在全面、充分评估疾病的基础上遵循个体化原则进行诊疗。部分难治性直肠肛周CD患者最终需要接受直肠切除(或结直肠切除)以及永久性造口。本文主要围绕难治性直肠肛周CD行直肠切除的术式选择和值得关注和讨论的几个问题展开论述,以期为临床工作提供参考。
Crohn′s disease(CD)is a chronic non⁃specific intestinal inflammatory disease with unknown etiology and pathogenesis.CD patients have high probability of developing perianal lesion,which is an independent factor for poor prognosis in CD patients.Diagnosis and treatment of CD patients with rectal and perianal lesions should follow the principle of individualization on the basis of comprehensive assessment.Part of CD patients with refractory rectal and perianal diseases eventually require proctectomy(or proctocolectomy)and permanent stoma.This review mainly focuses on the surgical option and consideration of proctectomy for refractory anorectal Crohn′s disease and key issues worthy of attention and discussion,in order to provide reference for clinical practice.
作者
陈文豪
丁召
Chen Wenhao;Ding Zhao(Department of Colorectal and Anal Surgery,Surgical Center of Inflammatory Bowel Disease,Clinical Center of Intestinal and Colorectal Diseases of Hubei Province,Hubei Key Laboratory of Intestinal and Colorectal Diseases,Quality Control Center of Colorectal and Anal Surgery of Health Commission of Hubei Province,Zhongnan Hospital of Wuhan University,Wuhan 430071,China)
出处
《中华炎性肠病杂志(中英文)》
2023年第3期233-238,共6页
Chinese Journal of Inflammatory Bowel Diseases
关键词
克罗恩病
肛周病变
直肠切除
术式选择
Crohn′s disease
Perianal disease
Proctectomy
Surgical option