摘要
目的:观察清瘿散治疗桥本氏甲状腺炎的临床疗效。方法:选取符合纳入标准的桥本氏甲状腺炎患者97例,随机分为两组,治疗组49例予中药清瘿散成方颗粒治疗,对照组48例予中药安慰剂成方颗粒治疗,观察12周,比较患者甲状腺自身抗体水平、生存质量评分(SF-36)、中医证候积分的变化。结果:治疗组总有效率91.8%,优于对照组的62.5%(P﹤0.05)。治疗后,治疗组TPOAb、TgAb均较治疗前下降(P﹤0.05),对照组TgAb较治疗前下降(P﹤0.05);治疗组TPOAb、TgAb明显优于对照组(P﹤0.05);治疗组的TPOAb和TgAb下降有效率均优于对照组(P﹤0.05)。治疗组SF-36量表各维度评分均较治疗前提高(P﹤0.05)。结论:清瘿散可缓解桥本氏甲状腺炎患者抗体紊乱,改善临床症状,提高生活质量。
Objective:To observe the clinical efficacy of Qingying powder on Hashimoto's thyroiditis.Methods:97 cases of eligible patients with Hashimoto's thyroiditis were selected and randomly divided into two groups.49 cases of treatment group were treated with Linfang granule of Chinese herbal medicine Qingying powder,while 48 cases of control group were treated with Linfang Granule of Chinese herbal medicine placebo.After observation for 12 weeks,the changes of thyroid autoantibody level,quality of life score(SF-36)and TCM syndrome score of patients were compared.Results:The total effective rate of treatment group was 91.8%,which was better than 62.5%of control group(P﹤0.05).After treatment:the levels of TPOAb and TgAb of treatment group were decreased compared with before treatment(P﹤0.05);TgAb of control group was decreased compared with before treatment(P﹤0.05);TPOAb and TgAb of treatment group were significantly better than those of control group(P﹤0.05);the effective rate of decreasing TPOAb and TgAb in treatment group was better than that in control group(P﹤0.05).The score of each dimension in SF-36 scale of treatment group was improved compared with before treatment(P﹤0.05).Conclusion:Qingying powder can relieve the antibody disorder of patients with Hashimoto's thyroiditis,improve the clinical symptoms and enhance the quality of life.
作者
徐伟
陶枫
程芳
Xu Wei;TAO Feng;CHENG Fang(Jinyang Community Health Service Center of Shanghai Pudong New Area,Shanghai 200136,China)
出处
《山西中医》
2023年第9期27-29,共3页
Shanxi Journal of Traditional Chinese Medicine
基金
上海市浦东新区卫生系统优秀青年医学人才培养计划项目(编号:PWRq2020-52)
上海市浦东新区卫生系统浦东名中医培养计划项目(编号:PWRzm2020-10)。
关键词
桥本氏甲状腺炎
清瘿散
中医药疗法
Hashimoto's thyroiditis
Qingying powder
therapy of TCM