体外反搏辅助治疗脑梗死的临床疗效及其对血液流变学指标的影响研究

Clinical effect of external counterpulsation on cerebral infarction and its influence on hemorheology

目的观察体外反搏辅助治疗脑梗死的临床疗效,并分析其对血液流变学指标的影响。方法研究时间在2018年12月-2022年5月,在此时段实施数据库资料调取,将80例符合录入标准的脑梗死患者作为样本,按照双色球数列分布的原则,将其划分为对照组、观察组,分别予以常规药物治疗、体外反搏辅助治疗,每组样本量为40例,评估临床疗效、NIHSS评分、脑血流储备情况、峰值流速情况及生活自理能力,比较两组治疗结果。结果临床疗效比较,数据在统计后,观察组有效率90.00%(36/40)高于对照组的70.00%(28/40),组间可见显著差异性(P<0.05);NIHSS评分比较,治疗前,组间评分未见差异性(P>0.05),治疗后,观察组为(4.32±1.16)分,评分低于对照组,组间可见差异性(P<0.05);脑血流储备情况比较,治疗前,指标在组间未见差异性(P>0.05),治疗后,观察组患侧脑血流值高于对照组,健侧脑血流值低于对照组,组间可见差异性(P<0.05);峰值流速情况比较,观察组(149.86±118.76)cm/s高于对照组(72.16±50.47)cm/s,组间可见差异性(P<0.05);生活自理能力比较,治疗前,数据统计以后,组间未见差异性(P>0.05),治疗后,数据显示观察组较高,组间可见差异性(P<0.05)。结论体外反搏辅助治疗脑梗死的疗效确切,有助于改善其血液流变学指标,加强患侧脑血流的储备,提高生活自理能力,促使神经功能恢复,改善预后,应用价值较高,建议临床推广应用。

Objective To observe the clinical efficacy of external counterpulsation in the treatment of cerebral infarction and analyze its influence on hemorheology.Methods The study period was from December 2018 to May 2022.During this period,the database data was retrieved,and 80 patients with cerebral infarction who met the entry criteria were taken as samples.According to the principle of dichromatic sequence distribution,they were divided into control group and observation group.They were given routine drug treatment and extracorporeal anti-pulsation adjuvant treatment respectively.The sample size of each group was divided into 40 cases,and the clinical efficacy,NIHSS score,cerebral blood flow reserve were evaluated,the peak flow rate and self-care ability were compared between the two groups.Results Compared with the clinical efficacy,after statistics,90.00%(36/40)of the observation group was higher than 70.00%(28/40)of the control group.There was significant difference between the groups,the result was P<0.05;compared with the NIHSS score,there was no difference between the groups before and after treatment,the result was P>0.05.After treatment,the score of the observation group was(4.32±1.16),lower than that of the control group,and the difference between the groups was visible,the result was P<0.05;comparison of cerebral blood flow reserve:before treatment,there was no difference between the two groups,the result was P>0.05.After treatment,the cerebral blood flow value of the affected side of the observation group was higher than that of the control group,and the cerebral blood flow value of the healthy side was lower than that of the control group,the difference between the two groups was visible,the result was P<0.05;compared with the peak flow rate,the observation group(149.86±118.76)cm/s was higher than the control group(72.16±50.47)cm/s,and there was significant difference between the groups,the result was P<0.05;self-care ability comparison:before treatment,after data statistics,there was no difference between the groups,the result was P>0.05.After treatment,the data showed that the observation group was higher,and the difference was visible between the groups,the result was P<0.05.Conclusion The curative effect of extracorporeal counterpulsation in the treatment of cerebral infarction is confirmed,which is helpful to improve its hemorheology index,strengthen the reserve of cerebral blood flow on the affected side,improve the ability of self-care,promote the recovery of nerve function,improve the prognosis,and has high application value.It is recommended to popularize and apply it in clinical medicine.