消化性溃疡复发的影响因素分析及健康教育的意义

Analysis of influencing factors of peptic ulcer recurrence and significance of health education

目的探讨消化性溃疡复发的相关影响因素及健康教育的应用效果。方法选取2019年1月-2021年6月期间于广东省第二中医院健康体检发现的237例消化性溃疡患者,对其进行为期1年的随访,分析所有患者的复发情况,并对消化性溃疡复发的各因素进行单因素及多因素Logistic回归分析。结果此研究内的237例消化性溃疡患者经随访发现,复发率为16.88%,其中胃溃疡占比最高,为62.50%,复合溃疡占比最低,为15.00%;两组年龄、合并糖尿病、合并高血压占比对比,差异无统计学意义(P>0.05);复发组男性患者、有吸烟史、有饮酒史占比均高于未复发组,差异有统计学意义(P<0.05);两组溃疡数目、焦虑、抑郁占比对比,差异无统计学意义(P>0.05);复发组溃疡最大直径(≥7mm)、终末幽门螺旋杆菌感染、有非甾体类抗炎药物应用史占比均高于未复发组,差异有统计学意义(P<0.05);经Logistic回归分析发现,男性患者、有吸烟史、有饮酒史、溃疡最大直径(≥7mm)、终末幽门螺旋杆菌感染、有非甾体类抗炎药物应用史均为导致消化性溃疡患者复发的相关影响因素(OR>1,P<0.05)。结论男性患者、有吸烟史、有饮酒史等均为导致消化性溃疡患者复发的相关影响因素,临床应指导患者戒烟、戒酒,养成良好生活习惯等,以降低消化性溃疡复发风险。

Objective To explore the related influencing factors of peptic ulcer recurrence and the application effect of continuous nursing.Methods A total of 237 patients with peptic ulcer treated in the Hospital from January 2019 to June 2021 were enrolled and followed up for one year.The recurrence of all patients was analyzed,and the factors of peptic ulcer recurrence were analyzed through univariate and multivariate logistic regression analysis.Results Through the follow-up visit of the 237 patients with peptic ulcers,it was found that the recurrence rate was 16.88%,of which the proportion of gastric ulcers was the highest at 62.50%and the proportion of complex ulcers was the lowest at 15.00%.There was no statistically significant difference in terms of age,diabetes complicated,hypertension complicated between the recurrent and the non-recurrent groups(P>0.05).The proportion of male patients with smoking history and drinking history in the recurrent group was higher than that in the non-recurrent group,and the difference was statistically significant(P<0.05).There was no significant difference in the number of ulcers,anxiety,and depression between the two group(P>0.05).The proportion of patients with ulcers with a maximum diameter of≥7mm,terminal Helicobacter pylori infection,and history of nonsteroidal anti-inflammatory drugs in the recurrent group were higher than that in the non-recurrent group,and the difference was statistically significant(P<0.05).Logistic regression analysis found that male gender,history of smoking,drinking history,maximum ulcer diameter(≥7mm),terminal Helicobacter pylori infection and history of nonsteroidal anti-inflammatory drugs were related factors for recurrence of peptic ulcer(OR>1,P<0.05).Conclusion Male gender,history of smoking,and history of drinking are all related influencing factors that lead to recurrence of peptic ulcer.Clinically,patients should be instructed to quit smoking,keep away from alcohol,and develop healthy habits to reduce the risk of recurrence of peptic ulcer.