子痫前期患者发生胎盘早剥的影响因素

Influencing factors of placental abruption in patients with preeclampsia

目的:分析子痫前期患者发生胎盘早剥的影响因素。方法:回顾性分析2019年5月至2020年10月该院收治的44例子痫前期发生胎盘早剥患者的临床资料,设为发生组;另选取同期该院收治的44例子痫前期患者的临床资料,设为未发生组。收集所有患者的一般资料,并采用Logistic回归分析影响子痫前期患者发生胎盘早剥的因素。结果:发生组年龄、分娩时孕周、分娩前BMI、初产妇、婚姻状态、文化程度、流产史、缴费方式、居住地、子痫前期家族遗传史、饮酒史、抽烟史占比与未发生组比较,差异均无统计学意义(P>0.05);发生组的CysC水平高于未发生组,APN水平低于未发生组,差异均有统计学意义(P<0.05);Logistic回归分析结果显示,血清CysC过表达、血清APN低表达均为影响子痫前期患者发生胎盘早剥的危险因素(P<0.05)。结论:血清CysC过表达、血清APN低表达均为影响子痫前期患者发生胎盘早剥的危险因素。

Objective:To analyze influencing factors of placental abruption in patients with preeclampsia.Methods:The clinical data of 44 patients with preeclampsia and placental abruption admitted to the hospital from May 2019 to October 2020 were retrospectively analyzed and they were set as occurrence group.In addition,the clinical data of 44 patients with preeclampsia admitted to the hospital during the same period were selected and set as non-occurrence group.The general information of all patients was collected.Logistic regression analysis was used to analyze the factors affecting placental abruption in the patients with preeclampsia.Results:There were no significant differences in the age,gestational age at delivery,BMI before delivery,primipara,marital status,education level,abortion history,payment method,place of residence and proportions of family genetic history of preeclampsia,drinking history and smoking history between the occurrence group and the non-occurrence group(P>0.05).The level of CysC in the occurrence group was higher than that in the non-occurrence group,the level of APN was lower than that in the non-occurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that serum CysC overexpression and serum APN low expression were risk factors for placental abruption in the patients with preeclampsia(P<0.05).Conclusions:The serum CysC overexpression and the serum APN low expression are the risk factors for placental abruption in the patients with preeclampsia.