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谷红注射液联合复方脑肽对缺血性脑梗死的有效性及安全性研究

Effect and Safety Study on Safflower and Aceglutamide Injection Combined with Compound Brain Peptide in Treatment of Ischemic Stroke
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摘要 目的研究分析谷红注射液联合复方脑肽对缺血性脑梗死患者的有效性及安全性。方法选取本院2020年10月-2022年6月收治的缺血性脑梗死患者84例为研究对象,根据患者用药不同进行分组,将42例运用常规抗血小板、他汀类药物、活血化瘀、营养神经等药物进行基础治疗的患者设为对照组,观察组患者42例,在对照组基础上加用谷红注射液与复方脑肽治疗。观察比较两组患者治疗有效性、神经功能缺损程度、日常生活能力、治疗安全性。结果与对照组比较,观察组治疗有效性更高,差异明显(P<0.05)。观察组治疗后意识水平、凝视、上肢运动、下肢运动、感觉、总分均比对照组低(P<0.05),具有明显差异。与对照组相比,观察组治疗后日常生活能力分值更高(P<0.05)。在治疗安全性方面,两组比较无明显差异(P>0.05)。结论缺血性脑梗死患者应用谷红注射液联合复方脑肽治疗的效果确切,不仅能够促进患者神经功能恢复,还可以增强患者日常生活能力,且不会明显提高不良反应发生率,值得临床推荐应用。 Objective To study and analyze effect and safety of safflower and aceglutamide Injection combined with compound brain peptide for patients with ischemic stroke.Methods The paper chose 84 patients with ischemic stroke admitted to our hospital from October 2020 to June 2022 as research objects,and divided them into groups based on medication.42 cases in control group were treated with basic treatment including routine antiplatelet and statin drugs,blood circulation and blood stasis and nerve nutrition,42 cases in observation group with safflower and aceglutamide Injection and compound brain peptide based on control group,(P<0.05).Treatment effect,degree of neurological impairment,daily living ability and treatment safety was observed and compared between two groups.Results Observation group had higher cuaritve effect than control group,with significant difference(P<0.05).After treatment,consciousness level,gaze,upper limb movement,lower limb movement,sensation degree and total scores of observation group were lower than control group,with significant difference(P<0.05).Observation group had higher scores of daily living ability than control group after treatment(P<0.05),indicating significant difference.In terms of treatment safety,there was no significant difference between two groups(P>0.05).Conclusion Combination of safflower and aceglutamide injection and compound brain peptide therapy can achieve accurate effect for ischemic stroke patients,can promote recovery of neurological function,enhance daily living ability without significantly increasing incidence of adverse reactions,which is worthy of clinical recommendation and application.
作者 张红燕 ZHANG Hongyan(Neurology Department,Sihong Zhongxin Hospital,Suqian,Jiangsu 223900)
出处 《智慧健康》 2023年第16期71-74,共4页 Smart Healthcare
关键词 缺血性脑梗死 谷红注射液 复方脑肽 有效性 安全性 Ischemic stroke Safflower and aceglutamide injection Compound brain peptide Effectiveness Safety
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