高警示药品说明书中特殊人群用药信息调查

Investigation on information of drug use for special populations in instructive labels of high-alert medica-tions

目的调查高警示药品说明书中特殊人群用药信息的标注情况,为合理用药提供参考。方法以河南省郑州市第七人民医院高警示药品为研究对象,对药品的说明书进行详细查阅,将其在特殊人群用药信息方面的标注情况进行统计分析。结果河南省郑州市第七人民医院在用的高警示药品共198种,其中分别有162、162、162、141、135、117份药品说明书对孕妇、哺乳期妇女、儿童、老年人、肝及肾功能不全者做了标注,分别占高警示药品品种数的81.8%、81.8%、81.8%、71.2%、68.2%、59.1%。结论高警示药品说明书在特殊人群用药方面的标注存在缺失,增加了特殊人群的用药风险。需要加强药品说明书中对特殊人群的用药标注,完善相关说明,增强用药安全性和合理性。

Objective To investigate the descriptive information of drug use for special populations in in-structive labels of high-alert medications,so as to provide reference for rational medication use.Methods We scrutinized the descriptive information on instructive labels of high-alert medications,as the target of this investi-gational study,from Zhengzhou Seventh People′s Hospital.The descriptive information of drug use in special pop-ulations was statistically analyzed.Results A total of 198 categories of high-alert medications were available Zhengzhou Seventh People′s Hospital,of which medication cautions were labeled for use in pregnant women(n=162),breast-feeding mothers(n=162),children(n=162),elderly people(n=141),and the individuals with hepatic(n=135)and renal insufficiency(n=117),accounting for 81.8%,81.8%,81.8%,71.2%,68.2%,and 59.1%of all categories of the high-alert medications,respectively.Conclusion Inadequate description as noted in the instruc-tive labels of high-alert medications for use in special populations would increase the medication risk among these individuals.Reinforced stipulations should be implemented on the labeling for medications in special populations with more details,so as to improve the safety and rationality of drug use.