摘要
克罗恩病(CD)是一种慢性非特异性胃肠道炎症性疾病。儿童CD起病隐匿,临床表现缺乏特异性,早期诊断困难,导致并发症、手术率和致残率增加。早期筛查和诊断、及时干预可改善患儿的治疗效果和预后,提高患儿生存质量。文章就儿童CD的早期筛查和诊断进展进行综述。
Crohn's disease(CD)is a chronic nonspecific gastrointestinal inflammatory disease.The onset of CD in children is insidious,the clinical manifestations are lack of specificity,and early diagnosis is difficult,which leads to the increased complications,surgical rates and disability rates.Early screening and diagnosis,timely intervention can improve the therapeutic effect and prognosis of children,and improve the life quality of children.This article reviews the progress of early screening and diagnosis of CD in children.
作者
汪陈慧(综述)
杨辉(审校)
WANG Chenhui;YANG Hui(Degestive Department,Children's Hospital Affiliated to Nanjing Medical University,Nanjing 210008,Jiangsu,China)
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2023年第9期708-714,共7页
Journal of Clinical Pediatrics
基金
南京市医学科技发展项目(No.YKK21153)。
关键词
克罗恩病
血清标志物
肠道微生物
代谢组学
儿童
Crohn's disease
serum marker
intestinal microorganisms
metabonomics
child