摘要
An organocatalytic asymmetric trifluoromethylthiolation of 3-aryl or 3-alkyloxindoles employing a trifluoromethyl-substituted thioperoxide as the electrophilic trifluoromethylthiolating reagent was described.Reactions occurred in good to excellent enantioselectivities to generate oxindoles with a SCF_(3)-substituted quaternary chiral center.
基金
The authors gratefully acknowledge the financial support from National Basic Research Program of China(2012CB821600)
the Key Program of Natural Science Foundation of China(21032006)
National Natural Science Foundation of China(21172245/21172244/21372247)and 100-talent program of SIOC.
