基于近红外光谱技术的脑血氧监测装置研究

Research on the Brain Blood Oxygen Monitoring Device Based on Near Infrared Spectroscopy

为了让医护人员尽早了解临床脑损伤患者术后的脑血氧变化情况,及时做出诊断和治疗,研究一款无创、实时、连续的监测脑血氧装置。基于近红外光谱技术(NIRS),设计了一款双波长光源(730nm、850nm)和双探测器的脑血氧监测装置;选取小巧、便携的贴片发光、光电二极管作为光源与探测器,设计跨阻放大电路、模拟滤波电路、光源驱动电路等硬件系统;编写简洁的GUI界面,利用脑血氧监测基本原理将脑血氧的实时变化值显示在上位机上。在前臂阻断实验中,组织血氧饱和度随阻断后呈现下降趋势,释放压力后又逐渐恢复至静息水平。在不同体位脑血氧实测实验中,倒牵状态下的脑组织血氧饱和度显著大于静息坐姿的值。实验结果表明,该装置可实时监测局部脑组织血氧的变化情况,初步验证了装置的可行性。

In order to enable medical staff to understand the changes in cerebral blood oxygen levels after surgery in patients with clinical brain injury as soon as possible,and to make timely diagnosis and treatment,a non-invasive,real-time,and continuous monitoring device for cerebral blood oxygen levels is proposed.This device is based on near-infrared spectroscopy(NIRS)technology and has designed a dual wavelength light source(730 nm,850 nm)and dual detector brain blood oxygen monitoring device;Select compact and portable SMD light emitting diodes and photodiodes as light sources and detectors,design hardware systems such as cross resistance amplification circuits,analog filtering circuits,and light source driver circuits;Write a concise GUI interface that utilizes the basic principles of cerebral blood oxygen mon-itoring to display real-time changes in cerebral blood oxygen on the upper computer.In the forearm occlusion experiment,tissue oxygen satura-tion showed a decreasing trend after occlusion,and gradually returned to resting levels after releasing pressure.In the experiment of measuring cerebral blood oxygen in different postures,the cerebral tissue blood oxygen saturation under reverse traction was significantly higher than that in resting sitting posture.The experimental results indicate that this device can monitor the changes in local brain tissue blood oxygen in real-time,preliminarily verifying the feasibility of the device.