前交叉韧带重建术后短期内移植体黏性变化

Short-Term Changes of Graft Viscosity after Anterior Cruciate Ligament Reconstruction

目的研究前交叉韧带重建(anterior cruciate ligament reconstruction,ACLR)术后短时间内移植体黏性的变化规律。方法选择6只雄性新西兰兔,以跟腱为移植体制作单侧膝关节ACLR动物模型。ACLR术后15 d将实验兔安乐死,取出移植体、健康的前交叉韧带(anterior cruciate ligament,ACL)和跟腱。测量移植体的截面积,分别进行0.1、1 MPa平衡条件的蠕变实验,并计算黏性系数,总结移植体的黏性变化规律,与健康ACL进行对比。结果移植体的截面积在手术后15 d内缓慢上升。ACL与移植体的黏性呈非线性变化。在不同应力下,黏性系数有较大差异。移植体黏性系数随ACLR术后时间呈下降趋势,但在低应力下更明显。结论本文建议,ACLR术后早期康复过程中,应使用助行器,降低步频,并避免踢、踹等对关节冲击的运动。

Objective To study the short-term variation patterns of graft viscosity after anterior cruciate ligament reconstruction(ACLR)surgery.Methods Six male New Zealand rabbits were selected.The ACLR animal model of unilateral knee was made with Achilles tendon as the graft.The experimental rabbits were euthanized 15 days after ACLR surgery,with removal of the graft,healthy anterior cruciate ligament(ACL)and Achilles tendon.The cross-sectional area and viscosity coefficient of the graft were measured,and the creep experiments were carried out under equilibrium conditions of 0.1 MPa and 1 MPa,respectively.The viscosity coefficent was calculated.Variation patterns of graft viscosity were summarize.The grafts were compared with healthy ACL.Results The cross-sectional area of the graft increased slowly within 15 days after ACLR surgery.The viscosity of ACL and graft changed nonlinearly.The viscosity coefficient was quite different under different stresses.The viscosity coefficient of the graft decreased with the time after ACLR surgery,which was more obviously under the condition of low stress.Conclusions It is suggested that in the early postoperative rehabilitation process of ACLR surgery,walking aids should be used,to reduce stride frequency and avoid kicking and other movements that impact the joints.