热敏灸治疗无先兆偏头痛:随机对照试验

Heat-sensitive moxibustion for migraine without aura:a randomized controlled trial

目的:比较热敏灸与温和灸治疗无先兆偏头痛的临床疗效。方法:将54例无先兆偏头痛患者随机分为观察组(27例,脱落2例)和对照组(27例,脱落2例)。两组均予基础西药治疗,对照组于患侧率谷、风池、阳陵泉行温和灸;观察组于患侧敏感度较高的穴位处(风池、率谷、太阳、太冲、阳陵泉等)进行探查,每次选择3个热敏感最强的腧穴行温和灸。两组均每日1次,5次为一疗程,共治疗2个疗程。分别于治疗前后比较两组患者偏头痛症状积分、疼痛视觉模拟量表(VAS)评分、偏头痛特异性生活质量评定问卷(MSQ)评分,并于治疗后评定两组临床疗效。结果:治疗后,两组患者偏头痛症状积分、VAS评分均较治疗前降低(P<0.01),MSQ评分均较治疗前升高(P<0.01);观察组偏头痛症状积分、VAS评分低于对照组(P<0.05),MSQ评分高于对照组(P<0.01)。观察组总有效率为92.0%(23/25),高于对照组的72.0%(18/25,P<0.05)。结论:热敏灸和温和灸均可有效缓解无先兆偏头痛患者临床症状、头痛程度,改善生活质量,热敏灸疗效优于温和灸。

Objective To compare the clinical effect between heat-sensitive moxibustion and mild moxibustion for migraine without aura.Methods A total of 54 patients with migraine without aura were randomized into an observation group(27 cases,2 cases dropped off)and a control group(27 cases,2 cases dropped off).The basic western medication treatment was adopted in the two groups.In the control group,mild moxibustion was applied at Shuaigu(GB 8),Fengchi(GB 20)and Yanglingquan(GB 34)on the affected side.In the observation group,the frequent acupoint areas of the affected side i.e.Shuaigu(GB 8),Fengchi(GB 20),Taiyang(EX-HN 5),Taichong(LR 3),Yanglingquan(GB 34)were determined,3 acupoints with strong heat-sensitive sensation were selected each time and mild moxibustion was adopted.The treatment was given once a day,5 times of treatment was as one course and 2 courses were required in the two groups.Before and after treatment,the scores of migraine symptom,visual analogue scale(VAS),migraine specific quality of life questionnaire(MSQ)were observed,and the clinical efficacy was evaluated after treatment in the two groups.Results After treatment,the scores of migraine symptom and VAS were decreased compared with those before treatment(P<0.01),while the MSQ scores were increased compared with those before treatment(P<0.01)in the two groups.After treatment,the scores of migraine symptom and VAS in the observation group were lower than those in the control group(P<0.05),while the MSQ score in the observation group was higher than that in the control group(P<0.01).The total effective rate was 92.0%(23/25)in the observation group,which was superior to 72.0%(18/25)in the control group(P<0.05).Conclusion Both heat-sensitive moxibustion and mild moxibustion can effectively alleviate the clinical symptoms,improve the headache degree and life quality in patients with migraine without aura,the clinical efficacy of heat-sensitive moxibustion is superior to that of mild moxibustion.