透明质酸诱导羟丙基纤维素相变

Hyaluronic acid induced phase transition of hydroxypropyl cellulose

通过与透明质酸(HA)的氢键作用,降低羟丙基纤维素(HPC)的相转变温度,也即低临界溶解温度(LCST),采用紫外可见分光光度计(UV-Vis)探究温度对HPC浊度的影响,考察大分子HA的浓度、分子量、HPC的浓度,溶液pH以及加入单体AA或者高分子PAA对于HPC相转变温度的影响。结果表明,在添加PAA的HA与HPC的三者混合溶液中,HPC可以达到更低的LCST,而且HA在酸性,碱性甚至是中性条件下,都可以改变HPC的相转变温度,HA可以有效降低HPC的相转变温度,可使其在较低温度下发生浊度变化,是可应用于智能窗户中改变透光度高效材料。

The phase transition temperature of hydroxypropyl cellulose(HPC),that is,the lower critical solution temperature(LCST),is reduced by hydrogen bonding with hyaluronic acid(HA).The turbidity change of the sample with temperature is investigated by using a variable temperature ultraviolet spectrophotometer(UV-Vis).The effect on the phase transition temperature of HPC is observed by changing the HA concentration,molecular weight,HPC concentration,solution pH,and the addition of monomer AA or polymer PAA.The results obtained that HPC can achieve lower LCST in the mixed solution of HA and HPC added with PAA.Moreover,HA can change the phase transition temperature of HPC under acidic,alkaline and even neutral conditions.HA has been proved to be an efficient material that can effectively reduce the phase transition temperature of HPC and change its turbidity at a lower temperature,and can be applied to smart windows to change the amount of light transmitted.