新型光致变色螺吡喃化合物的合成及研究

Synthesis and Research of Novel Photochromic Spiropyran Compounds

将萘胺与羧基螺吡喃进行酰胺化得到了一种新型的螺吡喃衍生物,通过核磁共振氢谱进行了结构确认,对中间体羧基吲哚和最终产物SP-N的合成条件进行了条件优化。当醋酸用量为40 mL,反应时间为18 h时,中间体的产率达到最大为40.1%,当n(三乙胺)∶n(萘胺)为1.5∶1时,酰胺化反应产率达到最大38%。

A new spiropyran derivative is obtained by amidation of naphthylamine with carboxy spiropyran.The structure is confirmed by 1H-NMR,the synthesis conditions of the intermediate indole and the final product SP-N are optimized.When the amount of acetic acid is 40 mL and the reaction time is 18 h,the maximum yield of the intermediate is 40.1%.When the molar ratio of triethylamine,naphthylamine is 1.5∶1,the maximum yield of the amidation reaction is 38%.