血必净联合抗菌药物治疗重症肺炎的临床效果

Clinical Effect of Xuebijing Combined with Antibiotics in Treatment of Severe Pneumonia

目的:探究血必净联合抗菌药物在重症肺炎患者中的临床治疗效果。方法:选取2021年1月—2022年12月前海人寿广西医院收治的60例重症肺炎患者为研究对象,根据按随机数字表法分为对照组(应用抗菌药物治疗)与研究组(应用血必净+抗菌药物治疗,各30例)。比较两组患者的治疗效果、炎性因子水平、血气指标及不良反应发生率。结果:治疗后,研究组治疗总有效率高于对照组,差异有统计学意义(P=0.020);研究组白细胞计数、C反应蛋白、血清降钙素原水平、动脉血二氧化碳分压低于对照组,动脉氧分压、氧合指数高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:血必净联合抗菌药物治疗重症肺炎患者效果较好,可改善机体炎性因子、血气参数以及患者肺部感染情况,安全性较高。

Objective:To explore the clinical effect of Xuebijing combined with antibiotics in patients with severe pneumonia.Methods:A total of 60 patients with severe pneumonia were selected at Qianhai Life Insurance Guangxi Hospital from January 2021 to December 2022,and they were divided into control group(treated with antibiotics)and research group(treated with Xuebijing+antibiotics)according to the random number table method,with 30 cases in each group.The treatment effect,inflammatory factor levels,blood gas indexes and incidence of adverse reactions were compared between the two groups.Results:After treatment,the total effective rate of the research group was higher than that of the control group,and the difference was statistically significant(P=0.020);the white blood cell count,C-reactive protein,serum procalcitonin level,and arterial blood carbon dioxide partial pressure of the research group were lower than those of the control group,the arterial oxygen partial pressure and oxygenation index were higher than those in the control group,and the arterial oxygen partial pressure and oxygenation index were higher than those in the control group,the differences were statistically significant(P<0.05);there was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Xuebijing combined with antibiotics in the treatment of severe pneumonia patients is effective,can improve the body inflammatory factors,blood gas parameters and patients with lung infection,high safety.