右美托咪定和咪达唑仑对小儿静脉吸入复合麻醉预防苏醒期躁动的效果比较

Effects of Dexmedetomidine and Midazolam on Agitation during Recovery from Intravenous Inhalation Anesthesia in Children

【目的】比较右美托咪定(Dex)和咪达唑仑对患儿静脉吸入复合麻醉预防麻醉苏醒期躁动的效果。【方法】选取2020年3月至2021年3月在本院接受静脉吸入复合麻醉的60例患儿,随机分为观察组与对照组,每组30例。对照组予以咪达唑仑麻醉,观察组予以Dex麻醉。比较两组麻醉时间、手术时间、苏醒时间及苏醒期不同时间点的躁动发生率。【结果】观察组麻醉时间、手术时间及苏醒时间与对照组比较,差异均无统计学意义(P>0.05);观察组在拔管后5 min、10 min、15 min、20 min时躁动发生率均低于对照组(P<0.05);观察组拔管即刻及拔管后30 min的躁动发生率与对照组比较,差异均无统计学意义(P>0.05)。【结论】小儿静脉吸入复合麻醉中应用Dex预防麻醉苏醒期躁动的效果优于咪达唑仑。

【Objective】To analyze the effect of dexmedetomidine(Dex)and midazolam on prevention of agitation(EA)during anesthesia recovery in children with intravenous inhalation combined anesthesia.【Methods】A total of 60 children in our hospital who received intravenous inhalation compound anesthesia from March 2020 to March 2021 were selected and divided into two groups according to anesthesia drugs,the control group(30 cases with Mida anesthesia)and the observation group(30 cases with Dex anesthesia).The anesthesia time,operation time,recovery time and the incidence of agitation at different time points during the recovery period were compared between the two groups.【Results】The anesthesia time,operation time and recovery time of the two groups were not statistically significant difference(P>0.05).The incidence of agitation at 5 min,10 min,15 min and 20 min after extubation in the observation group was lower than that in the control group(P<0.05).The incidence of agitation immediately and 30 min after extubation between the observation group and the control group was not statistically significant difference(P>0.05).【Conclusion】Dexmedetomidine is better than midazolam in preventing agitation in children with intravenous inhalation combined anesthesia.