头颈部软组织肉瘤放射治疗的回顾与展望

Radiotherapy for the head and neck soft tissue sarcomas:review and prospect

软组织肉瘤(STS)是来源于间叶组织的一类高度异质性的恶性肿瘤,最常见的发病部位依次是四肢(45%)、内脏(21%)和腹膜后(17%)。相较于其他部位,头颈部的软组织肉瘤发病率最低(5%),并且功能性器官较多,解剖结构更精细复杂,往往难以进行根治性手术治疗。因此,放射治疗在头颈部软组织肉瘤的治疗中,具有更加重要的地位。由于头颈部软组织肉瘤发病较少见,目前针对头颈部软组织肉瘤放疗的研究和关注均较少。本文对头颈部软组织肉瘤放疗的现状和临床证据做一综述,为临床实践提供参考。

Soft tissue sarcoma(STS)is a highly heterogeneous group of malignant tumors originating from mesenchymal tissues.The most common sites of STS are limbs(45%),viscera(21%)and retroperitoneum(17%).The incidence of head and neck soft tissue sarcomas(HNSTS)is the lowest(5%)compared with other areas of the body.Due to numerous functional organs and delicate and complex anatomical structures of the head and neck,it is often difficult to perform radical surgical treatment.Therefore,radiotherapy plays an important role in the treatment of HNSTS.Due to its low incidence,radiotherapy for HNSTS has been rarely studied and captivated little attention.In this article,the present situation and clinical evidence of radiotherapy for HNSTS were summarized,aiming to provide reference for clinical practice.