摘要
In December,2019,pneumonia triggered by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)surfaced in Wuhan,China.An acute respiratory illness named coronavirus disease 2019(COVID-19)is caused by a new coronavirus designated as SARS-CoV-2.COVID-19 has surfaced as a major pandemic in the 21st century as yet.The entire world has been affected by this virus.World Health Organization proclaimed COVID-19 pandemic as a public health emergency of international concern on January 30,2020.SARS-CoV-2 shares the same genome as coronavirus seen in bats.Therefore,bats might be its natural host of this virus.It primarily disseminates by means of the respiratory passage.Evidence revealed human-to-human transmission.Fever,cough,tiredness,and gastrointestinal illness are the manifestations in COVID-19-infected persons.Senior citizens are more vulnerable to infections which can lead to dangerous consequences.Various treatment strategies including antiviral therapies are accessible for the handling of this disease.In this review,we organized the most recent findings on COVID-19 history,origin,transmission,genome structure,replication,epidemiology,pathogenesis,clinical features,diagnosis,and treatment strategies.
