绿茶多酚疗愈保健作用研究进展

Research progress on the healing and health care effects of green tea polyphenols

本文综述近年来关于绿茶多酚对心血管、肺损伤、肝损伤、肾损伤、脑损伤、肿瘤、高血糖、高血脂、病毒感染、细菌感染、抑郁症、儿童性早熟、外伤、结肠炎等14个方面疾病的治疗与保健作用的研究进展。饮用绿茶能够降低心脑血管疾病的风险;可能通过抑制炎性细胞因子表达水平、提高抗氧化能力来保护肺部组织形态与结构的完整,减轻被动吸烟对肺部的损害;能够拮抗无机砷诱导的肝肾组织病理改变和功能性损伤;对大鼠缺血-再灌注氧化损伤肾脏具有保护作用;可通过抑制TLR4通路减轻蛛网膜下腔出血大鼠早期脑损伤;可有效抑制lnc RNA NEAT1促肿瘤干细胞特性,从而影响非小细胞肺癌增殖;对肥胖相关高血压患者的血压、胰岛素抵抗、炎症和氧化应激等均可显著改善;可以调节脂代谢平衡;对多种细菌和病毒有抑制作用;有抗抑郁作用;对肥胖女童肥胖指标和性发育指标均有改善作用;可促进伤口愈合及皮肤组织结构重塑;可以改善结肠炎症。绿茶多酚确实有很可靠的疗愈保健作用,展望未来绿茶多酚的药用价值、食用价值、经济价值能被深度开发。

We organize literature and then review the research progress in recent years on the therapeutic and health care effects of green tea polyphenols on 14 aspects of diseases,including cardiovascular,lung injury,liver injury,kidney injury,brain injury,tumor,hyperglycemia,hyperlipidemia,viral infections,bacterial infections,depression,precocious puberty in children,traumatic injuries,colitis,and so on.Drinking green tea can reduce the risk of cardiovascular and cerebrovascular diseases;may protect the morphological and structural integrity of lung tissues by inhibiting the expression level of inflammatory cytokines and improving the antioxidant capacity to protect the lungs from the damage caused by passive smoking;can antagonize the inorganic arsenic-induced histopathological changes in liver and kidney tissues and functional injuries;has a protective effect on the oxidative damage to the kidneys of rats with ischemia-reperfusion;can protect the kidneys from oxidative damage through inhibiting the TLR4 pathway it can reduce early brain damage in rats with subarachnoid hemorrhage;it can effectively inhibit lnc RNA NEAT1 tumor-promoting stem cell properties,thus affecting the proliferation of non-small cell lung cancer;it can significantly improve blood pressure,insulin resistance,inflammation,and oxidative stress in patients with obesity-associated hypertension;it can regulate the balance of lipid metabolism;it can have an inhibitory effect on a variety of bacteria and viruses;it has an antidepressant effect;it can improve both the indexes of obesity and sexual development in girls with obesity;it can improve the obesity index and sexual development index of obese girls;it can promote wound healing and skin tissue remodeling;it can improve the inflammation of the colon.Green tea polyphenols have very reliable healing health effects whose medicinal,food,and economic values are expected to be intensively developed in the future.