Parenteral iron therapy in children with iron defi ciency anemia

I read with interest the article by Mantadakis et al entitled"Intravenous iron sucrose for children with iron deficiency anemia:a single institution study".[1]The article has raised a very interesting issue.There are very few published studies on parenteral iron administration in pediatric practice for nonrenal indication.[2]Besides,because of reported hypersensitivity,pediatric hematologists are usually reluctant to give parenteral iron formulations.Finally,either European Medicines Agency or Food and Drug Administration does not approve most intravenous iron agents for pediatric use.Thereby,as opposed to countless oral iron preparations,there are only few intravenous iron products for children.