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Bioassay studies of cobalt (Ⅱ) complexes of modified diamine

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摘要 Coordination compounds of modified diamine,the basic unit of which are ethylenediamine,with that of Co(Ⅱ)are prepared.The modified diamines are ethylenediaceticacid(EDDA)and N,N,N,N-tetaraethylene-1,2-diamine(TEEDA).These diamines are characterized through ^(1)H-NMR,^(13)C-NMR,elemental analysis and IR techniques.Cobalt(Ⅱ)complexes of these two ligands were prepared and characterized by physical measurements including elemental analysis,IR,UVVisible,magnetic susceptibilities and conductance measurements.Antibacterial activities are also carried out in order to investigate the biological activity upon complexation.They were screened against four pathogenic bacteria like Escherichia coli,Pseudomonas aeroginosa,Klesbella pneumonia and Staphylococcus aureus.The results showed significant enhancement in activities.
出处 《Frontiers of Chemistry in China》 2011年第2期98-104,共7页 中国化学前沿(英文版)
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