妊娠期糖尿病患者血清中人软骨糖蛋白39、弹性蛋白酶抑制剂、血清促代谢因子的表达及其与胰岛素抵抗的关系

Expression of YKL-40,SerpinB1 and Betatrophin in serum of patients with gestational diabetes mellitus and their relationship with insulin resistance

研究妊娠期糖尿病(GDM)患者血清中人软骨糖蛋白39(YKL-40)、弹性蛋白酶抑制剂(SerpinB1)、血清促代谢因子(Betatrophin)的表达及其与胰岛素抵抗的关系。研究发现GDM患者血清中YKL-40、SerpinB1、betatrophin的表达与胰岛素抵抗呈现出显著的相关性,可为临床诊断提供科学依据。

To investigate the expression of human cartilage glycoprotein 39(YKL-40),elastase inhibitor(SerpinB1)and serum pro-metabolic factor(Betatrophin)in the serum of patients with gestational diabetes mellitus(GDM)and their relationship with insulin resistance.The expression of YKL-40,SerpinB1 and betatrophin in the serum of GDM patients showed a significant correlation with insulin resistance,which could provide a scientific basis for clinical diagnosis.