正向调强放疗和三维适形放疗对宫颈癌患者预后的影响

Effect of forward intensity modulated radiotherapy and three-dimensional conformal radiotherapy on the prognosis of patients with cervical cancer

目的探讨正向调强放疗和三维适形放疗对宫颈癌(CC)患者预后的影响。方法选择邹平市人民医院2019年8月至2020年8月收治的82例CC患者为研究对象,根据不同的治疗方法分为A组(n=41,正向调强放疗)与B组(n=41,三维适形放疗)。比较两组靶区剂量相关指标、危及器官受照射情况、治疗效果及预后情况。结果A组平均剂量、适形度指数高于B组(P<0.05);两组均匀性指数比较,差异无统计学意义(P>0.05);A组膀胱、小肠、直肠、左股骨头、右股骨头受照射范围小于B组(P<0.05);两组治疗总有效率和转移、复发及死亡率比较,差异无统计学意义(P>0.05)。结论正向调强放疗和三维适形放疗治疗CC的临床效果较好,其中正向调强放疗法在控制靶区剂量分布和减小危及器官受照射范围方面更具优势。

Objective To explore the effect of forward intensity modulated radiotherapy and three-dimensional conformal radiotherapy on the prognosis of patients with cervical cancer(CC).Methods A total of 82 patients with CC admitted to Zouping People’s Hospital from August 2019 to August 2020 were selected as the research objects.According to different treatment methods,they were divided into group A(n=41,forward intensity modulated radiotherapy)and group B(n=41,three-dimensional conformal radiotherapy).The target volu me dose related indicators,exposure of organs at risk,treatment effect and prognosis were compared between the two groups.Results The average dose and conformity index of group A were higher than those of group B(P<0.05).There was no significant difference in homogeneity index between the two groups(P>0.05).The exposure range of bladder,small intestine,rectum,left femoral head and right femoral head in group A was smaller than that in group B(P<0.05).There were no significant differences in the total effective rate and the rates of metastasis,recurrence,and death between the two groups(P>0.05).Conclusion Forward intensity modulated radiotherapy and three-dimensional conformal radiotherapy have good clinical effects in the treatment of CC,and forward intensity modulated radiotherapy has more advantages in controlling the dose distribution in the target volume and reducing the exp osure range of organs at risk.