苏合香丸结合颅内血肿微创抽吸引流术治疗自发性脑出血临床效果观察

Clinical Observation of Suhexiang Pill(苏合香丸)Combined with Minimally Invasive Extractive Flow for Intracranial Hematoma in Treatment of Spontaneous Intracerebral Hemorrhage

目的评估苏合香丸结合颅内血肿微创抽吸引流术治疗自发性脑出血临床效果。方法研究纳入自发性脑出血共计104例(2019年2月—2022年5月收治),以随机数字表法将纳入患者分成两组,分别为对照组(52例)与研究组(52例),对照组患者采取颅内血肿微创抽吸引流术治疗,研究组患者在颅内血肿微创抽吸引流术治疗基础上结合苏合香丸治疗,1丸/次,2次/d,连续用药10 d;观察临床疗效、并发症、治疗前后患者格拉斯哥晕迷指数(GCS)评分及美国国立卫生研究院卒中量表(NIHSS)评分及脑卒中专用生命质量量表(SS-QOL)评分变化、患者血肿消失时间与住院治疗时间。结果研究组患者治疗总有效率与对照组治疗总有效率比较[94.23%(45/52)vs 80.77%(42/52)](P<0.05);研究组患者总并发症率与对照组比较[3.85%(2/52)vs 15.38%(8/52)](P<0.05);治疗前,两组患者GCS评分、NIHSS评分与SS-QOL评分比较(P>0.05),治疗后各组患者GCS评分、NIHSS评分与SS-QOL评分均改善,研究组患者治疗后GCS评分、NIHSS评分与SS-QOL评分均优于对照组(P<0.05);研究组患者血肿消失时间与住院治疗时间均比对照组患者更短(P<0.05)。结论苏合香丸结合颅内血肿微创抽吸引流术治疗自发性脑出血临床效果显著,且并发症少,患者恢复快,生活质量提升,值得应用。

Objective To evaluate the clinical effect of Suhexiang Pill(苏合香丸)combined with minimally invasive suction flow for intracranial hematoma in the treatment of spontaneous intracerebral hemorrhage.Methods A total of 104 cases of spontaneous intracerebral hemorrhage(admitted from February 2019 to May 2022)were divided into two groups by random number table method:control group(52 cases)and study group(52 cases).The control group was treated with minimally invasive aspiration flow for intracerebral hematoma.Patients in the study group were treated with Suhexiang Pill,1 pill per time,2 times per day,continuously for 10 d,on the basis of minimally invasive aspiration and flow therapy for intracranial hematoma.The clinical efficacy,complications,changes of Glasgow Dizziness Index(GCS)score,National Institutes of Health Stroke Scale(NIHSS)score and stroke specific quality of life scale(SS-QOL)score before and after treatment,disappearance time of hematoma and hospitalization time.Results The total effective rate of the study group was compared with that of the control group[94.23%(45/52)vs 80.77%(42/52)](P<0.05).The total complication rate of the study group was compared with that of the control group[3.85%(2/52)vs 15.38%(8/52)](P<0.05).Before treatment,the GCS score,NIHSS score and SS-QOL score of two groups were compared(P>0.05).After treatment,the GCS score,NIHSS score and SS-QOL score of patients in each group were improved.The GCS score,NIHSS score and SS-QOL score of patients in the study group were better than those of the control group(P<0.05).The time of hematoma disappearance and hospitalization in the study group were shorter than those in the control group(P<0.05).Conclusion Suhexiang Pill combined with minimally invasive suction flow for intracranial hematoma in the treatment of spontaneous intracerebral hemorrhage has significant clinical effect,with fewer complications,rapid recovery and improved quality of life,which is worthy of application.