超声引导下椎板后阻滞联合塞来昔布在慢性原发性腰痛中的应用

Application of ultrasound-guided posterior laminar block combined with celecoxib in the treatment of chronic primary low back pain

目的观察超声引导下椎板后阻滞(RLB)联合塞来昔布治疗慢性原发性腰痛的有效性及安全性。方法选取该院2022年1-6月诊治的50例慢性原发性腰痛患者,按随机数字表法将其分为对照组和观察组,各25例。对照组口服塞来昔布治疗,观察组采用RLB联合口服塞来昔布治疗。对比2组患者治疗前后的疼痛数字评价量表(NRS)、魁北克腰痛障碍量表(QBPDS)评分,以及2组的治疗效果、不良反应发生率。结果与对照组比较,观察组患者治疗后NRS评分及QBPDS评分显著降低,治疗效果显著增加,差异均有统计学意义(P<0.01)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论超声引导下RLB联合塞来昔布治疗可快速缓解慢性原发性腰痛,且无明显不良反应。

Objective To observe the efficacy and safety of ultrasound-guided posterior laminar block(RLB)combined with celecoxib in the treatment of chronic primary low back pain.Methods A total of 50 pa-tients with chronic primary low back pain diagnosed and treated in the hospital from January to June 2022 were selected and randomly divided into the control group(group C)and the observation group(group T),with 25 cases in each group.The control group was treated with oral celecoxib,while the observation group was treated with RLB combined with oral celecoxib.The Numerical Rating Scale(NRS)and Quebec Back Pain Disability Scale(QBPDS)scores before and after treatment were compared between the two groups,as well as the effective rate and incidence of adverse reactions between the two groups.Results Compared with the con-trol group,the NRS score and QBPDS score of patients in the observation group at each time point after treat-ment were significantly decreased,and the rate of above significant effect was significantly increased(P<0.01),but there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Ultrasound-guided RLB combined with celecoxib therapy can quickly relieve chronic primary low back pain without obvious adverse reactions.