摘要
Dear Editor,As a conserved mechanism among eukaryotic organisms,RNA silencing is vital for suppressing gene expression at the transcriptional or posttranscriptional level to regulate multiple biological processes.Small interfering RNAs(si RNAs)generated by Dicer proteins integrate with Argonaute(AGO)to form an RNA-induced silencing complex(RISC),in which RNA/DNA could be degraded/methylated through a sequence-specific manner(Ding et al.,2004).
基金
supported by the National Key Research and Development Program of China(2022YFD1400800 and 2021YFA1300400)
the National Natural Science Foundation of China(32250001)。