CREMa overexpression decreases IL-2 production,induces a TH17 phenotype and accelerates autoimmunity
被引量:2
摘要
Dear Editor,External cytokines produced by cells of the innate immune system induce the dif-ferentiation of CD4+T cells into helper T cell subsets with distinct functions and cytokine profiles.Apart from TH1 and TH2 cells a third subset of helper T cells has been described,which is characterized by increased expression of IL-17A,IL-17F,IL-21 and IL-22(TH17 cells).
同被引文献16
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