健康管理模式辅助超声检查在早期甲状腺癌筛查中的应用价值分析

Analysis of the Value of Health Management Model-assisted Ultrasonography in the Screening of Early Thyroid Cancer

目的:探析健康管理模式辅助超声检查在早期甲状腺癌筛查中的应用价值。方法:选取2020年7月—2021年8月郑州市心血管病医院(郑州市第七人民医院健康体检科)行超声检查的4000例体检筛查者作为研究对象。通过筛查将确诊为甲状腺肿瘤患者根据肿瘤性质分为良性肿瘤组(n=274)、恶性肿瘤组(n=35)。所有体检者均行超声检查,确诊或高危患者需要联合健康管理模式辅助。统计甲状腺肿瘤患者一般资料、观察两组患者干预结局并对比两组患者甲状腺肿瘤超声特征。结果:恶性肿瘤组出现内部低回声(31例,占比88.57%)、血供增加(28例,占比80%)、肿块钙化(29例,占比82.86%)、边界模糊(27例,占比77.14%);良性肿瘤组出现内部低回声(45例,占比16.42%)、血供增加(34例,占比12.41%)、肿块钙化(31例,占比11.31%)、边界模糊(23例,占比8.39%)。恶性肿瘤组的各项超声特征概率明显高于良性肿瘤组,差异有统计学意义(χ^(2)=87.108、88.404、101.523、108.152,P<0.05)。随访2个月结果显示,274例良性肿瘤组患者中,进展为早期甲状腺癌者4例(进展率1.46%),其他患者经过有效健康管理及治疗后,病情得到控制;35例甲状腺癌患者中,3例甲状腺髓样癌(MTC)患者和2例甲状腺未分化癌(ATC)患者病情出现恶化,而其他患者经过有效健康管理及治疗后,癌细胞扩散得到延缓及控制。结论:健康管理模式辅助超声检查应用于早期甲状腺癌筛查中应用价值较高,可以鉴别甲状腺癌及良性肿瘤患者,有利于预防疾病发生及进展。

Objective:To explore the value of health management model-assisted ultrasonography in early thyroid cancer screening.Methods:The 4000 cases of physical examination screeners who underwent ultrasonography in hospitals from July 2020 to August 2021 were selected as study subjects,and patients diagnosed with thyroid tumors by screening were divided into benign tumor group(n=274)and malignant tumor group(n=35)according to the nature of the tumor.All physical examiners underwent ultrasonography,and confirmed or high-risk patients required joint health management mode of assistance.The general data of patients with thyroid tumor,observation of intervention outcomes in both groups,and comparison of ultrasound characteristics of thyroid tumor in both groups were counted.Results:The malignant tumor group showed internal hypoechogenicity(31 cases,88.57%),increased blood supply(28 cases,80%),calcification of the mass(29 cases,82.86%),and blurred borders(27 cases,77.14%).The benign tumor group showed internal hypoechogenicity(45 cases,16.42%),increased blood supply(34 cases,12.41%),calcification of the mass(31 cases,11.31%),and blurred borders(23 cases,8.39%).The probability of each ultrasound feature was significantly higher in the malignant tumor group than in the benign tumor group,and the difference was statistically significant(χ^(2)=87.108,88.404,101.523,108.152,P<0.05).The results of the 2-month follow-up showed that among 274 patients in the benign tumor group,4 patients progressed to early thyroid cancer(progression rate of 1.46%),while the other patients had their disease controlled after effective health management and treatment.Among the 35 thyroid cancer patients,3 patients with medullary thyroid carcinoma(MTC)and 2 patients with undifferentiated thyroid carcinoma(ATC)showed deterioration,while the other patients had delayed and controlled the spread of cancer cells after effective health management and treatment.Conclusion:Health management model-assisted ultrasonography is of high value in early thyroid cancer screening,which can identify patients with thyroid cancer and benign tumors and help prevent disease occurrence and progression.