三子养亲汤治疗咳嗽变异性哮喘(痰湿阻络型)的临床观察

A Clinical Study of Sanzi Yangqin Decoction in the Treatment of Coughvariant Asthma of Phlegm-Dampness Obstructing Collaterals

目的 探讨三子养亲汤治疗咳嗽变异性哮喘(CVA)患者的临床效果。方法 选择2020年1月—2022年3月于南通市中医院门诊就诊的60例CVA(痰湿阻络型)患者作为此次研究观察对象,按照随机信封盲选原则分为对照组(30例)和观察组(30例)。其中,对照组患者采用孟鲁司特钠片治疗,观察组患者采用三子养亲汤治疗,两组都连续治疗1个月。评价两组患者咳嗽、咳痰、胸闷脘痞、大便溏的中医证候评分,并对两组患者日间、夜间咳嗽评分进行评估,同时比较临床治疗有效性。结果 治疗后,两组中医证候评分均较治疗前降低(P <0.05,P <0.01),且观察组评分均低于对照组(P <0.05,P <0.01);两组日间、夜间咳嗽评分均较治疗前降低(P <0.05,P <0.01),且观察组评分均低于对照组(P <0.01)。观察组临床治疗总有效率(93.33%)高于对照组(70.00%,P <0.05)。结论 三子养亲汤可以有效改善CVA患者咳嗽、咳痰、胸闷脘痞和大便溏症状,提高临床治疗有效性,保证患者治疗效果,可推广应用。

Objective To explore the clinical efficacy of Sanzi Yangqin Decoction in the treatment of patients with cough-variant asthma(CVA).Methods Sixty CVA patients with the syndrome of phlegm-dampness obstructing collaterals who visited the outpatient department of Nantong Hospital of Traditional Chinese Medicine from January 2020 to March 2022 were selected as the observational subjects for this study.According to the random envelope blind selection principle,they were divided into a control group(30 cases)and an observation group(30 cases).Among them,patients in the control group were treated with montelukast sodium tablets,while those in the observation group were treated with Sanzi Yangqin Decoction.Both groups were treated continuously for one month.The traditional Chinese medicine(TCM)syndrome scores for cough,expectoration,chest tightness,abdominal distension,and loose stools were evaluated for both groups.The daytime and nighttime cough scores were assessed for both groups,and the clinical treatment effectiveness was compared.Results After treatment,the TCM syndrome scores for both groups decreased compared with those before treatment(P<0.05,P<0.01),and the observation group was lower than the control group(P<0.05,P<0.01).The daytime and nighttime cough scores for both groups decreased compared with those before treatment(P<0.05,P<0.01),and the observation group was lower than the control group(P<0.01).The total clinical treatment effective rate in the observation group was 93.33%,higher than 70.00%in the control group(P<0.05).Conclusion Sanzi Yangqin Decoction can effectively improve the symptoms of cough,expectoration,chest tightness,abdominal distension,and loose stools in patients with CVA,enhance the clinical treatment effectiveness,ensure the treatment outcomes for patients,and can be widely applied.