常州市无偿献血人群人类巨细胞病毒感染情况调查

Analysis of human cytomegalovirus infection among unpaid blood donors in Changzhou city of China

目的调查常州市无偿献血人群的人类巨细胞病毒(HCMV)流行情况,为建立常州市HCMV抗体阴性库人群提供依据。方法随机筛选1848例常州市无偿献血者血液标本,ELISA方法检测HCMV-IgM和HCMV-IgG。应用SPSS 21.0统计分析软件对献血人群的性别、年龄、血型、学历、职业与HCMV感染率间的关系进行卡方检验,以P<0.05为差异有统计学意义。结果常州市无偿献血人群HCMV-IgG、HCMV-IgM阳性率分别为96.59%(1785/1848)和0.49%(9/1848),不同性别、不同年龄、不同学历及不同职业间的HCMV-IgG阳性率差异有统计学意义。结论常州市无偿献血人群HCMV既往感率染很高,而HCMV近期感染率很低,与我国其他地区的数据有所不同,表明我国不同地区HCMV感染率存在差异。性别、年龄、学历、职业导致无偿献血人群HCMV感染率存在差异。

Objective To study human cytomegalovirus(HCMV)prevalence among unpaid blood do⁃nors in Changzhou city of China.Methods 1848 unpaid blood donors were randomly chosen in Chang⁃zhou city,serum HCMV-IgM and HCMV-IgG were tested by ELISA.The association between prevalence rate and the demographic characteristic such as gender,age,blood type,education,and occupation were ana⁃lyzed by SPSS21.0.The difference was statistically significant(P<0.05).Results The positive rates of HCMV-IgM and HCMV-IgG among unpaid blood donors in Changzhou city were separately 0.49%and 96.59%.There were significant differences of positive rates of HCMV-IgG at gender,age,education,and occupation.Conclusion The positive rates of HCMV-IgM and HCMV-IgG among unpaid blood donors in Changzhou city were different from other areas of China.Gender,age,education,and occupation caused differences of positive rates of HCMV among unpaid blood donors.