厌氧氨氧化细菌梯烷脂的研究进展

Research advances in ladderane lipids of anammox bacteria

厌氧氨氧化细菌(AnAOB)在地球氮循环和环境污染治理中扮演着重要角色.AnAOB含有独特的梯烷脂,其核心结构是3或5个线性串联的环丁烷基团.至今尚未发现梯烷脂存在于其他细菌中,而且其生物合成通路和生理功能仍然未知.本文对AnAOB梯烷脂的发现、结构、性质、种类、合成及其应用进行了系统综述,并对梯烷脂的前沿问题和未来研究方向进行了讨论与展望.

Anaerobic ammonium-oxidizing bacteria(AnAOB)play an important role in the global nitrogen cycle and environmental pollution control.AnAOB contain unique ladderane lipids,whose key structure is three or five linearly concatenated cyclobutane moieties.Ladderane lipids have not been found in other bacteria so far,and their biosynthetic pathway and physiological function remain unknown.In this work,the advances in the discovery,structure,properties,types,applications,and synthesis of AnAOB ladderane lipids were comprehensively reviewed,and the current issues and prospected future research directions were discussed.