全身麻醉联合硬膜外麻醉在宫颈癌患者中的麻醉效果及对应激反应的影响研究

Effects of general anesthesia combined with epidural anesthesia on stress response in patients with cervical cancer

目的探讨宫颈癌患者采用全身麻醉联合硬膜外麻醉的效果。方法选取63例宫颈癌患者,根据麻醉方法不同分为对照组(31例)与研究组(32例)。对照组予以全身麻醉,研究组予以全身麻醉联合硬膜外麻醉。比较两组麻醉效果。结果对照组麻醉优良率为80.65%,研究组麻醉优良率为100%,研究组麻醉优良率高于对照组,差异具有统计学意义(P<0.05)。麻醉前,两组收缩压(SBP)、舒张压(DBP)、心率(HR)及脉搏,血氧饱和度(SpO_(2))指标比较,差异无统计学意义(P>0.05);麻醉后,研究组DBP、SBP及HR指标低于对照组,SpO_(2)指标高于对照组,差异具有统计学意义(P<0.05)。研究组患者麻醉时间、清醒时间及语言功能恢复时间均短于对照组,差异具有统计学意义(P<0.05)。结论相比单纯采用全身麻醉,联合硬膜外麻醉在宫颈癌手术治疗中,麻醉效果更为显著,手术中能有效减少患者的应激反应,值得临床推广。

Objective To investigate the effect of general anesthesia combined with epidural anesthesia in patients with cervical cancer.Methods 63 patients with cervical cancer were selected and divided into control group(31 cases)and study group(32 cases)according to different anesthesia methods.The control group was given general anesthesia,and the study group was given general anesthesia combined with epidural anesthesia.The anesthetic effect of the two groups was compared.Results The excellent and good rate of anesthesia in the control group was 80.65%,and that in the study group was 100%,which was higher than that in the control group,and the difference was statistically significant(P<0.05).Before anesthesia,systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR)and blood oxygen saturation(SpO_(2))were not significantly different between the two groups(P>0.05).After anesthesia,DBP,SBP and HR indexes in the study group were lower than those in the control group,and SpO_(2) indexes were higher than those in the control group,with statistical significance(P<0.05).The anesthesia time,waking time and speech function recovery time of the study group were shorter than those of the control group,and the differences were statistically significant(P<0.o5).Conclusion Compared with general anesthesia alone,combined epidural anesthesia has a more significant anesthetic effect in the surgical treatment of cervical cancer,which can effectively reduce the stress response of patients and is worthy of clinical promotion.