经尿道前列腺电切术治疗前列腺增生的效果及对PSA、PVR的影响

Effect of transurethral resection of the prostate in the treatment of prostatic hyperplasia and its influences on PSA and PVR

目的 分析经尿道前列腺电切术治疗前列腺增生的效果及对前列腺特异抗原(PSA)与残余尿量(PVR)的影响。方法 选取2019年3月至2021年3月收治的112例前列腺增生患者,根据随机数字表法将其分为对照组和观察组,各56例。对照组予以传统开放手术,观察组予以经尿道前列腺电切术。比较两组的治疗效果。结果 观察组的术中失血量少于对照组,膀胱冲洗时间、手术时间、尿管留置时间及住院时间均短于对照组(P<0.05)。术后7 d,观察组的PSA与表皮生长因子(EGF)水平低于对照组,前列环素(PGI2)水平高于对照组(P<0.05)。术后6个月,观察组的PVR低于对照组,膀胱顺应性(BC)、最大尿流率(Qmax)及性生活质量调查量表-生活质量维度(SLQQ-QOL)、国际勃起功能问卷-5(IIEF-5)评分均高于对照组(P<0.05)。观察组的并发症总发生率低于对照组(P<0.05)。结论 经尿道前列腺电切术治疗前列腺增生患者的效果显著。

Objective To analyze the effect of transurethral resection of the prostate in the treatment of prostatic hyperplasia and its influences on prostate specific antigen(PSA)and residual urine volume(PVR).Methods A total of 112 patients with prostatic hyperplasia admitted from March 2019 to March 2021 were selected and divided into control group and observation group according to random number table method,with 56 cases in each group.The control group received traditional open surgery,and the observation group received transurethral resection of the prostate.The therapeutic effects of the two groups were compared.Results The intraoperative blood loss in the observation group was less than that in the control group,and the bladder irrigation time,surgical time,urinary catheter indwelling time and hospital stay were shorter than those in the control group(P<0.05).At 7 d after surgery,the PSA and epidermal growth factor(EGF)levels in the observation group were lower than those in the control group,while the prostacyclin(PGI2)level was higher than that in the control group(P<0.05).At 6 months after surgery,the PVR in the observation group was lower than that in the control group,and the bladder compliance(BC),Qmax,the Sexual Life Quality Questionnaire-Quality of Life(SLQQ-QOL)and International Index of Erectile Function-5(IIEF-5)scores of the observation group were higher than those of the control group(P<0.05).The total incidence of complications of the observation group was lower than that of the control group(P<0.05).Conclusion Transurethral resection of the prostate has a significantly effect in the treatment of patients with prostatic hyperplasia.