摘要
精神分裂症是一种以认知、思维、情感、行为等多方面显著异常为特征的精神疾病,是最常见的重性精神疾病之一,给个人、家庭以及社会带来严重困扰。近年来针对精神分裂症患者的表观遗传学研究,DNA甲基化是主要的研究方向之一。综述近年来DNA甲基化与精神分裂症的研究进展,以期为精神分裂症症的进一步研究提供新的思路及参考价值。
Schizophrenia is a mental disorder characterized by significant abnormalities in cognition,thinking,emotion,and behavior.It is one of the most common severe mental disorders and causes serious distress to individuals,families,and society.In recent years,epigenetic studies focusing on DNA methylation have been conducted to understand schizophrenia.This review summarizes the research progress on DNA methylation and schizophrenia in recent years,aiming to provide new insights and reference value for further research on schizophrenia.
作者
尹文卅
卢玉梅
佟金莲
聂胜洁
阮冶
YIN Wensa;LU Yumei;TONG Jinlian;NIE shengjie;RUAN Ye(Dept.of Medical Administration,The Psychiatric Hospital of Yunnan Province;The Mental Health Prevention and Treatment Center of Yunnan Province;The Mental Health Center Affiliated to Kunming Medical University,Kunming Yunnan 650224;School of Forensic Medicine,Kunming Medical University,Kunming Yunnan 650500;Dept.of Postgraduate,Kunming Medical University,Kunming Yunnan 650500,China)
出处
《昆明医科大学学报》
CAS
2023年第8期145-150,共6页
Journal of Kunming Medical University
基金
国家自然科学基金资助项目(31860300)
昆明市卫生健康委员会卫生科研课题项目(2022-03-09-002)。
