摘要
卒中后失语(post-stroke aphasia,PSA)是卒中后常见的言语功能障碍,至少累及1/3的卒中患者,且对患者生活及工作造成严重不良影响。现有的干预措施包括言语和语言康复治疗、药物治疗以及非侵袭性脑刺激技术,后者主要包括经颅磁刺激和经颅直流电刺激(transcranial direct current stimulation,tDCS)。tDCS可通过促进PSA的自我修复、调节神经递质水平以及抑制炎症等机制对PSA产生积极影响。文章从tDCS对PSA自我恢复机制的影响以及治疗方面进行了综述。
Post-stroke aphasia(PSA)is a common speech disorder after stroke,involving at least 1/3 of stroke patients,and causing serious adverse effects on their lives and work.The available intervention measures include speech and language rehabilitation therapy,drug therapy,and non-invasive brain stimulation technology.The latter mainly includes transcranial magnetic stimulation and transcranial direct current stimulation(tDCS).tDCS can have a positive impact on PSA by promoting its self-repair,regulating the level of neurotransmitters,and inhibiting inflammation.This article reviews the effect of tDCS on the self-recovery mechanism of PSA and its treatment.
作者
孙思奇
董斌
Sun Siqi;Dong Bin(Department of Neurology,Binhu District,the Third Affiliated Hospital of Anhui Medical University(Hefei First People's Hospital),Hefei 230000,China)
出处
《国际脑血管病杂志》
2023年第5期384-389,共6页
International Journal of Cerebrovascular Diseases
基金
2020年度安徽医科大学校科研基金(2020xkj237)
合肥市第七周期临床重点培育专科。
关键词
卒中
失语
经颅直流电刺激
Stroke
Aphasia
Transcranial direct current stimulation
